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Lack of p53 decreases basal oxidative stress levels in the brain through upregulation of thioredoxin-1, biliverdin reductase-A, manganese superoxide dismutase, and nuclear factor kappa-B.
Barone E, Cenini G, Sultana R, Di Domenico F, Fiorini A, Perluigi M, Noel T, Wang C, Mancuso C, St Clair DK, Butterfield DA. Barone E, et al. Among authors: wang c. Antioxid Redox Signal. 2012 Jun 15;16(12):1407-20. doi: 10.1089/ars.2011.4124. Epub 2012 Feb 21. Antioxid Redox Signal. 2012. PMID: 22229939 Free PMC article.
Elevated glutathione is not sufficient to protect against doxorubicin-induced nuclear damage in heart in multidrug resistance-associated protein 1 (Mrp1/Abcc1) null mice.
Deng J, Coy D, Zhang W, Sunkara M, Morris AJ, Wang C, Chaiswing L, St Clair D, Vore M, Jungsuwadee P. Deng J, et al. Among authors: wang c. J Pharmacol Exp Ther. 2015 Nov;355(2):272-9. doi: 10.1124/jpet.115.225490. Epub 2015 Sep 9. J Pharmacol Exp Ther. 2015. PMID: 26354996 Free PMC article.
Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice.
Liu Y, Zhang C, Li Z, Wang C, Jia J, Gao T, Hildebrandt G, Zhou D, Bondada S, Ji P, St Clair D, Liu J, Zhan C, Geiger H, Wang S, Liang Y. Liu Y, et al. Among authors: wang c, wang s. Stem Cell Reports. 2017 Apr 11;8(4):991-1004. doi: 10.1016/j.stemcr.2017.02.009. Epub 2017 Mar 16. Stem Cell Reports. 2017. PMID: 28330618 Free PMC article.
Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A.
Oben KZ, Alhakeem SS, McKenna MK, Brandon JA, Mani R, Noothi SK, Jinpeng L, Akunuru S, Dhar SK, Singh IP, Liang Y, Wang C, Abdel-Latif A, Stills HF Jr, St Clair DK, Geiger H, Muthusamy N, Tohyama K, Gupta RC, Bondada S. Oben KZ, et al. Among authors: wang c. Oncotarget. 2017 Aug 24;8(44):77436-77452. doi: 10.18632/oncotarget.20497. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100399 Free PMC article.
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