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Aurora-A mediated phosphorylation of LDHB promotes glycolysis and tumor progression by relieving the substrate-inhibition effect.
Cheng A, Zhang P, Wang B, Yang D, Duan X, Jiang Y, Xu T, Jiang Y, Shi J, Ding C, Wu G, Sang Z, Wu Q, Wang H, Wu M, Zhang Z, Pan X, Pan YY, Gao P, Zhang H, Zhou CZ, Guo J, Yang Z. Cheng A, et al. Among authors: wang h, wang b. Nat Commun. 2019 Dec 5;10(1):5566. doi: 10.1038/s41467-019-13485-8. Nat Commun. 2019. PMID: 31804482 Free PMC article.
SS18 regulates pluripotent-somatic transition through phase separation.
Kuang J, Zhai Z, Li P, Shi R, Guo W, Yao Y, Guo J, Zhao G, He J, Xu S, Wu C, Yu S, Zhou C, Wu L, Qin Y, Cai B, Li W, Wu Z, Li X, Chu S, Yang T, Wang B, Cao S, Li D, Zhang X, Chen J, Liu J, Pei D. Kuang J, et al. Among authors: wang b. Nat Commun. 2021 Jul 2;12(1):4090. doi: 10.1038/s41467-021-24373-5. Nat Commun. 2021. PMID: 34215745 Free PMC article.
The NuRD complex cooperates with SALL4 to orchestrate reprogramming.
Wang B, Li C, Ming J, Wu L, Fang S, Huang Y, Lin L, Liu H, Kuang J, Zhao C, Huang X, Feng H, Guo J, Yang X, Guo L, Zhang X, Chen J, Liu J, Zhu P, Pei D. Wang B, et al. Nat Commun. 2023 May 18;14(1):2846. doi: 10.1038/s41467-023-38543-0. Nat Commun. 2023. PMID: 37208322 Free PMC article.
BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling.
Yu S, Zhou C, Cao S, He J, Cai B, Wu K, Qin Y, Huang X, Xiao L, Ye J, Xu S, Xie W, Kuang J, Chu S, Guo J, Liu H, Pang W, Guo L, Zeng M, Wang X, Luo R, Li C, Zhao G, Wang B, Wu L, Chen J, Liu J, Pei D. Yu S, et al. Among authors: wang x, wang b. Nat Cell Biol. 2020 Jun;22(6):651-662. doi: 10.1038/s41556-020-0516-x. Epub 2020 May 11. Nat Cell Biol. 2020. PMID: 32393886
Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Jdp2-Jhdm1b-Mkk6-Glis1-Nanog-Essrb-Sall4.
Wang B, Wu L, Li D, Liu Y, Guo J, Li C, Yao Y, Wang Y, Zhao G, Wang X, Fu M, Liu H, Cao S, Wu C, Yu S, Zhou C, Qin Y, Kuang J, Ming J, Chu S, Yang X, Zhu P, Pan G, Chen J, Liu J, Pei D. Wang B, et al. Among authors: wang x, wang y. Cell Rep. 2019 Jun 18;27(12):3473-3485.e5. doi: 10.1016/j.celrep.2019.05.068. Cell Rep. 2019. PMID: 31216469 Free article.
MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening.
Xing G, Liu Z, Huang L, Zhao D, Wang T, Yuan H, Wu Y, Li L, Long Q, Zhou Y, Hao Z, Liu Y, Lu J, Li S, Zhu J, Wang B, Wang J, Liu J, Chen J, Pei D, Liu X, Chen K. Xing G, et al. Among authors: wang j, wang t, wang b. Cell Death Differ. 2022 May;29(5):1042-1054. doi: 10.1038/s41418-021-00902-z. Epub 2021 Nov 24. Cell Death Differ. 2022. PMID: 34815549 Free PMC article.
AP-1 activity is a major barrier of human somatic cell reprogramming.
Liu Y, He J, Chen R, Liu H, Chen J, Liu Y, Wang B, Guo L, Pei D, Wang J, Liu J, Chen J. Liu Y, et al. Among authors: wang j, wang b. Cell Mol Life Sci. 2021 Aug;78(15):5847-5863. doi: 10.1007/s00018-021-03883-x. Epub 2021 Jun 28. Cell Mol Life Sci. 2021. PMID: 34181046
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