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FGF7-FGFR2 autocrine signaling increases growth and chemoresistance of fusion-positive rhabdomyosarcomas.
Milton CI, Selfe J, Aladowicz E, Man SYK, Bernauer C, Missiaglia E, Walters ZS, Gatz SA, Kelsey A, Generali M, Box G, Valenti M, de Haven-Brandon A, Galiwango D, Hayes A, Clarke M, Izquierdo E, Gonzalez De Castro D, Raynaud FI, Kirkin V, Shipley JM. Milton CI, et al. Among authors: walters zs. Mol Oncol. 2022 Mar;16(6):1272-1289. doi: 10.1002/1878-0261.13145. Epub 2021 Dec 18. Mol Oncol. 2022. PMID: 34850536 Free PMC article.
Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy.
Tonelli R, McIntyre A, Camerin C, Walters ZS, Di Leo K, Selfe J, Purgato S, Missiaglia E, Tortori A, Renshaw J, Astolfi A, Taylor KR, Serravalle S, Bishop R, Nanni C, Valentijn LJ, Faccini A, Leuschner I, Formica S, Reis-Filho JS, Ambrosini V, Thway K, Franzoni M, Summersgill B, Marchelli R, Hrelia P, Cantelli-Forti G, Fanti S, Corradini R, Pession A, Shipley J. Tonelli R, et al. Among authors: walters zs. Clin Cancer Res. 2012 Feb 1;18(3):796-807. doi: 10.1158/1078-0432.CCR-11-1981. Epub 2011 Nov 7. Clin Cancer Res. 2012. PMID: 22065083
Epigenetic Targets in Synovial Sarcoma: A Mini-Review.
Hale R, Sandakly S, Shipley J, Walters Z. Hale R, et al. Front Oncol. 2019 Oct 18;9:1078. doi: 10.3389/fonc.2019.01078. eCollection 2019. Front Oncol. 2019. PMID: 31681608 Free PMC article. Review.
Pharmacological EZH2 inhibition combined with retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells.
O'Brien E, Tse C, Tracy I, Reddin I, Selfe J, Gibson J, Tapper W, Pengelly RJ, Gao J, Aladowicz E, Petts G, Thway K, Popov S, Kelsey A, Underwood TJ, Shipley J, Walters ZS. O'Brien E, et al. Among authors: walters zs. Clin Epigenetics. 2023 Oct 19;15(1):167. doi: 10.1186/s13148-023-01583-w. Clin Epigenetics. 2023. PMID: 37858275 Free PMC article.
The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx).
Ciarapica R, De Salvo M, Carcarino E, Bracaglia G, Adesso L, Leoncini PP, Dall'Agnese A, Walters ZS, Verginelli F, De Sio L, Boldrini R, Inserra A, Bisogno G, Rosolen A, Alaggio R, Ferrari A, Collini P, Locatelli M, Stifani S, Screpanti I, Rutella S, Yu Q, Marquez VE, Shipley J, Valente S, Mai A, Miele L, Puri PL, Locatelli F, Palacios D, Rota R. Ciarapica R, et al. Among authors: walters zs. Oncogene. 2014 Aug 7;33(32):4173-84. doi: 10.1038/onc.2013.471. Epub 2013 Nov 11. Oncogene. 2014. PMID: 24213577
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