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The use of human induced pluripotent stem cells to screen for developmental toxicity potential indicates reduced potential for non-combusted products, when compared to cigarettes.
Simms L, Rudd K, Palmer J, Czekala L, Yu F, Chapman F, Trelles Sticken E, Wieczorek R, Bode LM, Stevenson M, Walele T. Simms L, et al. Among authors: walele t. Curr Res Toxicol. 2020 Nov 15;1:161-173. doi: 10.1016/j.crtox.2020.11.001. eCollection 2020 Jun 10. Curr Res Toxicol. 2020. PMID: 34345845 Free PMC article.
The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols.
Czekala L, Chapman F, Simms L, Rudd K, Trelles Sticken E, Wieczorek R, Bode LM, Pani J, Moelijker N, Derr R, Brandsma I, Hendriks G, Stevenson M, Walele T. Czekala L, et al. Among authors: walele t. Mutagenesis. 2021 May 31;36(2):129-142. doi: 10.1093/mutage/geaa033. Mutagenesis. 2021. PMID: 33769537 Free PMC article.
A randomised, open-label, cross-over clinical study to evaluate the pharmacokinetic profiles of cigarettes and e-cigarettes with nicotine salt formulations in US adult smokers.
O'Connell G, Pritchard JD, Prue C, Thompson J, Verron T, Graff D, Walele T. O'Connell G, et al. Among authors: walele t. Intern Emerg Med. 2019 Sep;14(6):853-861. doi: 10.1007/s11739-019-02025-3. Epub 2019 Feb 2. Intern Emerg Med. 2019. PMID: 30712148 Free PMC article. Clinical Trial.
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