Walczak H - Search Results

1

Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis.

Bolik J, Krause F, Stevanovic M, Gandraß M, Thomsen I, Schacht SS, Rieser E, Müller M, Schumacher N, Fritsch J, Wichert R, Galun E, Bergmann J, Röder C, Schafmayer C, Egberts JH, Becker-Pauly C, Saftig P, Lucius R, Schneider-Brachert W, Barikbin R, Adam D, Voss M, Hitzl W, Krüger A, Strilic B, Sagi I, Walczak H, Rose-John S, Schmidt-Arras D. Bolik J, et al. Among authors: walczak h. J Exp Med. 2022 Jan 3;219(1):e20201039. doi: 10.1084/jem.20201039. Epub 2021 Dec 17. J Exp Med. 2022. PMID: 34919140 Free PMC article.

2

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2.

Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, Krammer PH, Walczak H. Sprick MR, et al. Among authors: walczak h. Immunity. 2000 Jun;12(6):599-609. doi: 10.1016/s1074-7613(00)80211-3. Immunity. 2000. PMID: 10894160 Free article.

3

CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells.

Trauzold A, Wermann H, Arlt A, Schütze S, Schäfer H, Oestern S, Röder C, Ungefroren H, Lampe E, Heinrich M, Walczak H, Kalthoff H. Trauzold A, et al. Among authors: walczak h. Oncogene. 2001 Jul 12;20(31):4258-69. doi: 10.1038/sj.onc.1204559. Oncogene. 2001. PMID: 11464292

4

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

Sprick MR, Rieser E, Stahl H, Grosse-Wilde A, Weigand MA, Walczak H. Sprick MR, et al. Among authors: walczak h. EMBO J. 2002 Sep 2;21(17):4520-30. doi: 10.1093/emboj/cdf441. EMBO J. 2002. PMID: 12198154 Free PMC article.

5

Washburn B, Weigand MA, Grosse-Wilde A, Janke M, Stahl H, Rieser E, Sprick MR, Schirrmacher V, Walczak H. Washburn B, et al. Among authors: walczak h. J Immunol. 2003 Feb 15;170(4):1814-21. doi: 10.4049/jimmunol.170.4.1814. J Immunol. 2003. PMID: 12574346

6

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.

Haas TL, Emmerich CH, Gerlach B, Schmukle AC, Cordier SM, Rieser E, Feltham R, Vince J, Warnken U, Wenger T, Koschny R, Komander D, Silke J, Walczak H. Haas TL, et al. Among authors: walczak h. Mol Cell. 2009 Dec 11;36(5):831-44. doi: 10.1016/j.molcel.2009.10.013. Mol Cell. 2009. PMID: 20005846 Free article.

7

The linear ubiquitin chain assembly complex forms part of the TNF-R1 signalling complex and is required for effective TNF-induced gene induction and prevents TNF-induced apoptosis.

Emmerich CH, Schmukle AC, Haas TL, Gerlach B, Cordier SM, Rieser E, Walczak H. Emmerich CH, et al. Among authors: walczak h. Adv Exp Med Biol. 2011;691:115-26. doi: 10.1007/978-1-4419-6612-4_12. Adv Exp Med Biol. 2011. PMID: 21153315 No abstract available.

8

Linear ubiquitination: a newly discovered regulator of cell signalling.

Rieser E, Cordier SM, Walczak H. Rieser E, et al. Among authors: walczak h. Trends Biochem Sci. 2013 Feb;38(2):94-102. doi: 10.1016/j.tibs.2012.11.007. Epub 2013 Jan 17. Trends Biochem Sci. 2013. PMID: 23333406 Review.

9

Nuclear death receptor TRAIL-R2 inhibits maturation of let-7 and promotes proliferation of pancreatic and other tumor cells.

Haselmann V, Kurz A, Bertsch U, Hübner S, Olempska-Müller M, Fritsch J, Häsler R, Pickl A, Fritsche H, Annewanter F, Engler C, Fleig B, Bernt A, Röder C, Schmidt H, Gelhaus C, Hauser C, Egberts JH, Heneweer C, Rohde AM, Böger C, Knippschild U, Röcken C, Adam D, Walczak H, Schütze S, Janssen O, Wulczyn FG, Wajant H, Kalthoff H, Trauzold A. Haselmann V, et al. Among authors: walczak h. Gastroenterology. 2014 Jan;146(1):278-90. doi: 10.1053/j.gastro.2013.10.009. Epub 2013 Oct 9. Gastroenterology. 2014. PMID: 24120475

10

HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death.

Peltzer N, Rieser E, Taraborrelli L, Draber P, Darding M, Pernaute B, Shimizu Y, Sarr A, Draberova H, Montinaro A, Martinez-Barbera JP, Silke J, Rodriguez TA, Walczak H. Peltzer N, et al. Among authors: walczak h. Cell Rep. 2014 Oct 9;9(1):153-165. doi: 10.1016/j.celrep.2014.08.066. Epub 2014 Oct 2. Cell Rep. 2014. PMID: 25284787 Free article.

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