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IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility.
Song R, Gao Y, Dozmorov I, Malladi V, Saha I, McDaniel MM, Parameswaran S, Liang C, Arana C, Zhang B, Wakeland B, Zhou J, Weirauch MT, Kottyan LC, Wakeland EK, Pasare C. Song R, et al. Among authors: wakeland ek. Cell Rep. 2021 Mar 23;34(12):108891. doi: 10.1016/j.celrep.2021.108891. Cell Rep. 2021. PMID: 33761354 Free PMC article.
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.
Raj P, Rai E, Song R, Khan S, Wakeland BE, Viswanathan K, Arana C, Liang C, Zhang B, Dozmorov I, Carr-Johnson F, Mitrovic M, Wiley GB, Kelly JA, Lauwerys BR, Olsen NJ, Cotsapas C, Garcia CK, Wise CA, Harley JB, Nath SK, James JA, Jacob CO, Tsao BP, Pasare C, Karp DR, Li QZ, Gaffney PM, Wakeland EK. Raj P, et al. Among authors: wakeland ek, wakeland be. Elife. 2016 Feb 15;5:e12089. doi: 10.7554/eLife.12089. Elife. 2016. PMID: 26880555 Free PMC article.
Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus.
Raj P, Song R, Zhu H, Riediger L, Jun DJ, Liang C, Arana C, Zhang B, Gao Y, Wakeland BE, Dozmorov I, Zhou J, Kelly JA, Lauwerys BR, Guthridge JM, Olsen NJ, Nath SK, Pasare C, van Oers N, Gilkeson G, Tsao BP, Gaffney PM, Gregersen PK, James JA, Zuo X, Karp DR, Li QZ, Wakeland EK. Raj P, et al. Among authors: wakeland ek, wakeland be. Genome Biol. 2020 Nov 19;21(1):281. doi: 10.1186/s13059-020-02184-z. Genome Biol. 2020. PMID: 33213505 Free PMC article.
RAD51 interconnects between DNA replication, DNA repair and immunity.
Bhattacharya S, Srinivasan K, Abdisalaam S, Su F, Raj P, Dozmorov I, Mishra R, Wakeland EK, Ghose S, Mukherjee S, Asaithamby A. Bhattacharya S, et al. Among authors: wakeland ek. Nucleic Acids Res. 2017 May 5;45(8):4590-4605. doi: 10.1093/nar/gkx126. Nucleic Acids Res. 2017. PMID: 28334891 Free PMC article.
226 results