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Targeting alternative splicing as a new cancer immunotherapy-phosphorylation of serine arginine-rich splicing factor (SRSF1) by SR protein kinase 1 (SRPK1) regulates alternative splicing of PD1 to generate a soluble antagonistic isoform that prevents T cell exhaustion.
Wahid M, Pratoomthai B, Egbuniwe IU, Evans HR, Babaei-Jadidi R, Amartey JO, Erdelyi V, Yacqub-Usman K, Jackson AM, Morris JC, Patel PM, Bates DO. Wahid M, et al. Cancer Immunol Immunother. 2023 Dec;72(12):4001-4014. doi: 10.1007/s00262-023-03534-z. Epub 2023 Nov 16. Cancer Immunol Immunother. 2023. PMID: 37973660 Free PMC article.
Interplay in galectin expression predicts patient outcomes in a spatially restricted manner in PDAC.
Abudu O, Nguyen D, Millward I, Manning JE, Wahid M, Lightfoot A, Marcon F, Merard R, Margielewska-Davies S, Roberts K, Brown R, Powell-Brett S, Nicol SM, Zayou F, Croft WD, Pearce H, Moss P, Iqbal AJ, McGettrick HM. Abudu O, et al. Among authors: wahid m. Biomed Pharmacother. 2024 Mar;172:116283. doi: 10.1016/j.biopha.2024.116283. Epub 2024 Feb 20. Biomed Pharmacother. 2024. PMID: 38377735 Free article.
Cardioprotective and hypotensive mechanistic insights of hydroethanolic extract of Cucumis melo L. kernels in isoprenaline-induced cardiotoxicity based on metabolomics and in silico electrophysiological models.
Wahid M, Saqib F, Abbas G, Shah S, Alshammari A, Albekairi TH, Ali A, Khurm M, Mubarak MS. Wahid M, et al. Front Pharmacol. 2024 Jan 29;14:1277594. doi: 10.3389/fphar.2023.1277594. eCollection 2023. Front Pharmacol. 2024. PMID: 38348351 Free PMC article.
227 results