Wagner EJ - Search Results

1

Integrator is a global promoter-proximal termination complex.

Wagner EJ, Tong L, Adelman K. Wagner EJ, et al. Mol Cell. 2023 Feb 2;83(3):416-427. doi: 10.1016/j.molcel.2022.11.012. Epub 2023 Jan 11. Mol Cell. 2023. PMID: 36634676 Free PMC article. Review.

2

A subset of Drosophila integrator proteins is essential for efficient U7 snRNA and spliceosomal snRNA 3'-end formation.

Ezzeddine N, Chen J, Waltenspiel B, Burch B, Albrecht T, Zhuo M, Warren WD, Marzluff WF, Wagner EJ. Ezzeddine N, et al. Among authors: wagner ej. Mol Cell Biol. 2011 Jan;31(2):328-41. doi: 10.1128/MCB.00943-10. Epub 2010 Nov 15. Mol Cell Biol. 2011. PMID: 21078872 Free PMC article.

3

Integrator regulates transcriptional initiation and pause release following activation.

Gardini A, Baillat D, Cesaroni M, Hu D, Marinis JM, Wagner EJ, Lazar MA, Shilatifard A, Shiekhattar R. Gardini A, et al. Among authors: wagner ej. Mol Cell. 2014 Oct 2;56(1):128-139. doi: 10.1016/j.molcel.2014.08.004. Epub 2014 Sep 4. Mol Cell. 2014. PMID: 25201415 Free PMC article.

4

Integrator: surprisingly diverse functions in gene expression.

Baillat D, Wagner EJ. Baillat D, et al. Among authors: wagner ej. Trends Biochem Sci. 2015 May;40(5):257-64. doi: 10.1016/j.tibs.2015.03.005. Epub 2015 Apr 13. Trends Biochem Sci. 2015. PMID: 25882383 Free PMC article. Review.

5

Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance.

Wu Y, Albrecht TR, Baillat D, Wagner EJ, Tong L. Wu Y, et al. Among authors: wagner ej. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4394-4399. doi: 10.1073/pnas.1616605114. Epub 2017 Apr 10. Proc Natl Acad Sci U S A. 2017. PMID: 28396433 Free PMC article.

6

Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module.

Albrecht TR, Shevtsov SP, Wu Y, Mascibroda LG, Peart NJ, Huang KL, Sawyer IA, Tong L, Dundr M, Wagner EJ. Albrecht TR, et al. Among authors: wagner ej. Nucleic Acids Res. 2018 May 4;46(8):4241-4255. doi: 10.1093/nar/gky100. Nucleic Acids Res. 2018. PMID: 29471365 Free PMC article.

7

The Integrator complex cleaves nascent mRNAs to attenuate transcription.

Tatomer DC, Elrod ND, Liang D, Xiao MS, Jiang JZ, Jonathan M, Huang KL, Wagner EJ, Cherry S, Wilusz JE. Tatomer DC, et al. Among authors: wagner ej. Genes Dev. 2019 Nov 1;33(21-22):1525-1538. doi: 10.1101/gad.330167.119. Epub 2019 Sep 17. Genes Dev. 2019. PMID: 31530651 Free PMC article.

8

The Integrator Complex Attenuates Promoter-Proximal Transcription at Protein-Coding Genes.

Elrod ND, Henriques T, Huang KL, Tatomer DC, Wilusz JE, Wagner EJ, Adelman K. Elrod ND, et al. Among authors: wagner ej. Mol Cell. 2019 Dec 5;76(5):738-752.e7. doi: 10.1016/j.molcel.2019.10.034. Mol Cell. 2019. PMID: 31809743 Free PMC article.

9

Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination.

Huang KL, Jee D, Stein CB, Elrod ND, Henriques T, Mascibroda LG, Baillat D, Russell WK, Adelman K, Wagner EJ. Huang KL, et al. Among authors: wagner ej. Mol Cell. 2020 Oct 15;80(2):345-358.e9. doi: 10.1016/j.molcel.2020.08.016. Epub 2020 Sep 22. Mol Cell. 2020. PMID: 32966759 Free PMC article.

10

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.

Replogle JM, Saunders RA, Pogson AN, Hussmann JA, Lenail A, Guna A, Mascibroda L, Wagner EJ, Adelman K, Lithwick-Yanai G, Iremadze N, Oberstrass F, Lipson D, Bonnar JL, Jost M, Norman TM, Weissman JS. Replogle JM, et al. Among authors: wagner ej. Cell. 2022 Jul 7;185(14):2559-2575.e28. doi: 10.1016/j.cell.2022.05.013. Epub 2022 Jun 9. Cell. 2022. PMID: 35688146 Free PMC article.

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