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Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
Conlon TM, John-Schuster G, Heide D, Pfister D, Lehmann M, Hu Y, Ertüz Z, Lopez MA, Ansari M, Strunz M, Mayr C, Angelidis I, Ciminieri C, Costa R, Kohlhepp MS, Guillot A, Günes G, Jeridi A, Funk MC, Beroshvili G, Prokosch S, Hetzer J, Verleden SE, Alsafadi H, Lindner M, Burgstaller G, Becker L, Irmler M, Dudek M, Janzen J, Goffin E, Gosens R, Knolle P, Pirotte B, Stoeger T, Beckers J, Wagner D, Singh I, Theis FJ, de Angelis MH, O'Connor T, Tacke F, Boutros M, Dejardin E, Eickelberg O, Schiller HB, Königshoff M, Heikenwalder M, Yildirim AÖ. Conlon TM, et al. Among authors: wagner d. Nature. 2020 Dec;588(7836):151-156. doi: 10.1038/s41586-020-2882-8. Epub 2020 Nov 4. Nature. 2020. PMID: 33149305 Free PMC article.
Impairment of Immunoproteasome Function by Cigarette Smoke and in Chronic Obstructive Pulmonary Disease.
Kammerl IE, Dann A, Mossina A, Brech D, Lukas C, Vosyka O, Nathan P, Conlon TM, Wagner DE, Overkleeft HS, Prasse A, Rosas IO, Straub T, Krauss-Etschmann S, Königshoff M, Preissler G, Winter H, Lindner M, Hatz R, Behr J, Heinzelmann K, Yildirim AÖ, Noessner E, Eickelberg O, Meiners S. Kammerl IE, et al. Among authors: wagner de. Am J Respir Crit Care Med. 2016 Jun 1;193(11):1230-41. doi: 10.1164/rccm.201506-1122OC. Am J Respir Crit Care Med. 2016. PMID: 26756824
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.
Baarsma HA, Skronska-Wasek W, Mutze K, Ciolek F, Wagner DE, John-Schuster G, Heinzelmann K, Günther A, Bracke KR, Dagouassat M, Boczkowski J, Brusselle GG, Smits R, Eickelberg O, Yildirim AÖ, Königshoff M. Baarsma HA, et al. J Exp Med. 2017 Jan;214(1):143-163. doi: 10.1084/jem.20160675. Epub 2016 Dec 15. J Exp Med. 2017. PMID: 27979969 Free PMC article.
Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.
Baarsma HA, Skronska-Wasek W, Mutze K, Ciolek F, Wagner DE, John-Schuster G, Heinzelmann K, Günther A, Bracke KR, Dagouassat M, Boczkowski J, Brusselle GG, Smits R, Eickelberg O, Yildirim AÖ, Königshoff M. Baarsma HA, et al. J Exp Med. 2017 Feb;214(2):565. doi: 10.1084/jem.2016067501052017c. Epub 2017 Jan 9. J Exp Med. 2017. PMID: 28069639 Free PMC article. No abstract available.
Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.
Poobalasingam T, Yates LL, Walker SA, Pereira M, Gross NY, Ali A, Kolatsi-Joannou M, Jarvelin MR, Pekkanen J, Papakrivopoulou E, Long DA, Griffiths M, Wagner D, Königshoff M, Hind M, Minelli C, Lloyd CM, Dean CH. Poobalasingam T, et al. Among authors: wagner d. Dis Model Mech. 2017 Apr 1;10(4):409-423. doi: 10.1242/dmm.028175. Epub 2017 Feb 24. Dis Model Mech. 2017. PMID: 28237967 Free PMC article.
Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease.
Skronska-Wasek W, Mutze K, Baarsma HA, Bracke KR, Alsafadi HN, Lehmann M, Costa R, Stornaiuolo M, Novellino E, Brusselle GG, Wagner DE, Yildirim AÖ, Königshoff M. Skronska-Wasek W, et al. Am J Respir Crit Care Med. 2017 Jul 15;196(2):172-185. doi: 10.1164/rccm.201605-0904OC. Am J Respir Crit Care Med. 2017. PMID: 28245136
2,931 results