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Case Report: Arterial Wall Inflammation in Atherosclerotic Cardiovascular Disease is Reduced by Olamkicept (sgp130Fc).
Schulte DM, Waetzig GH, Schuett H, Marx M, Schulte B, Garbers C, Lokau J, Vlacil AK, Schulz J, Seoudy AK, Schieffer B, Rosenstiel P, Seeger M, Laudes M, Rose-John S, Lützen U, Grote K, Schreiber S. Schulte DM, et al. Among authors: waetzig gh. Front Pharmacol. 2022 Jun 9;13:758233. doi: 10.3389/fphar.2022.758233. eCollection 2022. Front Pharmacol. 2022. PMID: 35754497 Free PMC article.
Therapeutic Interleukin-6 Trans-signaling Inhibition by Olamkicept (sgp130Fc) in Patients With Active Inflammatory Bowel Disease.
Schreiber S, Aden K, Bernardes JP, Conrad C, Tran F, Höper H, Volk V, Mishra N, Blase JI, Nikolaus S, Bethge J, Kühbacher T, Röcken C, Chen M, Cottingham I, Petri N, Rasmussen BB, Lokau J, Lenk L, Garbers C, Feuerhake F, Rose-John S, Waetzig GH, Rosenstiel P. Schreiber S, et al. Among authors: waetzig gh. Gastroenterology. 2021 Jun;160(7):2354-2366.e11. doi: 10.1053/j.gastro.2021.02.062. Epub 2021 Mar 2. Gastroenterology. 2021. PMID: 33667488 Free article. Clinical Trial.
Tocilizumab does not block interleukin-6 (IL-6) signaling in murine cells.
Lokau J, Kleinegger F, Garbers Y, Waetzig GH, Grötzinger J, Rose-John S, Haybaeck J, Garbers C. Lokau J, et al. Among authors: waetzig gh. PLoS One. 2020 May 4;15(5):e0232612. doi: 10.1371/journal.pone.0232612. eCollection 2020. PLoS One. 2020. PMID: 32365119 Free PMC article.
Reply.
Schreiber S, Nikolaus S, Waetzig GH, Rosenstiel P. Schreiber S, et al. Among authors: waetzig gh. Gastroenterology. 2018 Jun;154(8):2275-2276. doi: 10.1053/j.gastro.2018.05.016. Epub 2018 May 8. Gastroenterology. 2018. PMID: 29750908 No abstract available.
The IL-6-neutralizing sIL-6R-sgp130 buffer system is disturbed in patients with type 2 diabetes.
Aparicio-Siegmund S, Garbers Y, Flynn CM, Waetzig GH, Gouni-Berthold I, Krone W, Berthold HK, Laudes M, Rose-John S, Garbers C. Aparicio-Siegmund S, et al. Among authors: waetzig gh. Am J Physiol Endocrinol Metab. 2019 Aug 1;317(2):E411-E420. doi: 10.1152/ajpendo.00166.2019. Epub 2019 Jun 25. Am J Physiol Endocrinol Metab. 2019. PMID: 31237452 Free article.
52 results