Wade RC - Search Results

1

Biochemical network-based drug-target prediction.

Klipp E, Wade RC, Kummer U. Klipp E, et al. Among authors: wade rc. Curr Opin Biotechnol. 2010 Aug;21(4):511-6. doi: 10.1016/j.copbio.2010.05.004. Epub 2010 Jun 14. Curr Opin Biotechnol. 2010. PMID: 20554441

2

SYCAMORE--a systems biology computational analysis and modeling research environment.

Weidemann A, Richter S, Stein M, Sahle S, Gauges R, Gabdoulline R, Surovtsova I, Semmelrock N, Besson B, Rojas I, Wade R, Kummer U. Weidemann A, et al. Bioinformatics. 2008 Jun 15;24(12):1463-4. doi: 10.1093/bioinformatics/btn207. Epub 2008 May 7. Bioinformatics. 2008. PMID: 18463116

3

Concerted simulations reveal how peroxidase compound III formation results in cellular oscillations.

Gabdoulline RR, Kummer U, Olsen LF, Wade RC. Gabdoulline RR, et al. Among authors: wade rc. Biophys J. 2003 Sep;85(3):1421-8. doi: 10.1016/S0006-3495(03)74574-3. Biophys J. 2003. PMID: 12944259 Free PMC article.

4

Organism-adapted specificity of the allosteric regulation of pyruvate kinase in lactic acid bacteria.

Veith N, Feldman-Salit A, Cojocaru V, Henrich S, Kummer U, Wade RC. Veith N, et al. Among authors: wade rc. PLoS Comput Biol. 2013;9(7):e1003159. doi: 10.1371/journal.pcbi.1003159. Epub 2013 Jul 25. PLoS Comput Biol. 2013. PMID: 23946717 Free PMC article.

5

Recent progress in molecular simulation methods for drug binding kinetics.

Nunes-Alves A, Kokh DB, Wade RC. Nunes-Alves A, et al. Among authors: wade rc. Curr Opin Struct Biol. 2020 Oct;64:126-133. doi: 10.1016/j.sbi.2020.06.022. Epub 2020 Aug 6. Curr Opin Struct Biol. 2020. PMID: 32771530 Review.

6

Prediction of drug binding affinities by comparative binding energy analysis.

Ortiz AR, Pisabarro MT, Gago F, Wade RC. Ortiz AR, et al. Among authors: wade rc. J Med Chem. 1995 Jul 7;38(14):2681-91. doi: 10.1021/jm00014a020. J Med Chem. 1995. PMID: 7629807

7

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.

Schuetz DA, de Witte WEA, Wong YC, Knasmueller B, Richter L, Kokh DB, Sadiq SK, Bosma R, Nederpelt I, Heitman LH, Segala E, Amaral M, Guo D, Andres D, Georgi V, Stoddart LA, Hill S, Cooke RM, De Graaf C, Leurs R, Frech M, Wade RC, de Lange ECM, IJzerman AP, Müller-Fahrnow A, Ecker GF. Schuetz DA, et al. Among authors: wade rc. Drug Discov Today. 2017 Jun;22(6):896-911. doi: 10.1016/j.drudis.2017.02.002. Epub 2017 Apr 13. Drug Discov Today. 2017. PMID: 28412474 Review.

8

Prediction of the Drug-Target Binding Kinetics for Flexible Proteins by Comparative Binding Energy Analysis.

Nunes-Alves A, Ormersbach F, Wade RC. Nunes-Alves A, et al. Among authors: wade rc. J Chem Inf Model. 2021 Jul 26;61(7):3708-3721. doi: 10.1021/acs.jcim.1c00639. Epub 2021 Jul 1. J Chem Inf Model. 2021. PMID: 34197096

9

A Protocol to Use Comparative Binding Energy Analysis to Estimate Drug-Target Residence Time.

Ganotra GK, Nunes-Alves A, Wade RC. Ganotra GK, et al. Among authors: wade rc. Methods Mol Biol. 2021;2266:171-186. doi: 10.1007/978-1-0716-1209-5_10. Methods Mol Biol. 2021. PMID: 33759127

10

Bridging from molecular simulation to biochemical networks.

Stein M, Gabdoulline RR, Wade RC. Stein M, et al. Among authors: wade rc. Curr Opin Struct Biol. 2007 Apr;17(2):166-72. doi: 10.1016/j.sbi.2007.03.014. Epub 2007 Mar 28. Curr Opin Struct Biol. 2007. PMID: 17395455 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

277 results

Search Page