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Page 1
Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production.
Hu LY, Lei HJ, Du D, Johnson TR, Fedij V, Kostlan C, Yue WS, Lovdahl M, Li JJ, Carroll M, Dettling D, Asbill J, Fan C, Wade K, Pocalyko D, Lapham K, Yalamanchili R, Samas B, Vrieze D, Ciotti S, Krieger-Burke T, Sliskovic D, Welgus H. Hu LY, et al. Among authors: wade k. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5693-7. doi: 10.1016/j.bmcl.2007.07.059. Epub 2007 Aug 19. Bioorg Med Chem Lett. 2007. PMID: 17766112
Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications.
Li JJ, Iula DM, Nguyen MN, Hu LY, Dettling D, Johnson TR, Du DY, Shanmugasundaram V, Van Camp JA, Wang Z, Harter WG, Yue WS, Boys ML, Wade KJ, Drummond EM, Samas BM, Lefker BA, Hoge GS, Lovdahl MJ, Asbill J, Carroll M, Meade MA, Ciotti SM, Krieger-Burke T. Li JJ, et al. J Med Chem. 2008 Nov 13;51(21):7010-4. doi: 10.1021/jm8009316. Epub 2008 Oct 16. J Med Chem. 2008. PMID: 18921992
Pantolactams as androgen receptor antagonists for the topical suppression of sebum production.
Sexton KE, Barrett S, Bridgwood K, Carroll M, Dettling D, Du D, Fakhoury S, Fedij V, Hu LY, Kostlan C, Pocalyko D, Raheja N, Smith Y, Shanmugasundaram V, Wade K. Sexton KE, et al. Among authors: wade k. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5230-3. doi: 10.1016/j.bmcl.2011.07.048. Epub 2011 Jul 23. Bioorg Med Chem Lett. 2011. PMID: 21831636
Comparison of artificial sebum with human and hamster sebum samples.
Lu GW, Valiveti S, Spence J, Zhuang C, Robosky L, Wade K, Love A, Hu LY, Pole D, Mollan M. Lu GW, et al. Among authors: wade k. Int J Pharm. 2009 Feb 9;367(1-2):37-43. doi: 10.1016/j.ijpharm.2008.09.025. Epub 2008 Sep 24. Int J Pharm. 2009. PMID: 18929636
A validated LC/MS/MS method for the quantification of pyrrole-2,3,5-tricarboxylic acid (PTCA), a eumelanin specific biomarker, in human skin punch biopsies.
Szekely-Klepser G, Wade K, Woolson D, Brown R, Fountain S, Kindt E. Szekely-Klepser G, et al. Among authors: wade k. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Nov 5;826(1-2):31-40. doi: 10.1016/j.jchromb.2005.08.002. Epub 2005 Aug 31. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 16139575
452 results