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Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers.
Listro R, Marra A, Cavalloro V, Rossino G, Linciano P, Rossi D, Casali E, De Amici M, Mazzeo G, Longhi G, Fusè M, Dondio G, Pellavio G, Laforenza U, Schepmann D, Wünsch B, Collina S. Listro R, et al. Among authors: wunsch b. J Pharm Biomed Anal. 2024 Feb 15;239:115902. doi: 10.1016/j.jpba.2023.115902. Epub 2023 Dec 14. J Pharm Biomed Anal. 2024. PMID: 38101238 Free article.
Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[18F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA Receptors.
Korff M, Chaudhary A, Li Y, Zhou X, Zhao C, Rong J, Chen J, Xiao Z, Elghazawy NH, Sippl W, Davenport AT, Daunais JB, Wang L, Abate C, Ahmed H, Crowe R, Schmidt TJ, Liang SH, Ametamey SM, Wünsch B, Haider A. Korff M, et al. Among authors: wunsch b. J Med Chem. 2023 Dec 14;66(23):16018-16031. doi: 10.1021/acs.jmedchem.3c01441. Epub 2023 Nov 18. J Med Chem. 2023. PMID: 37979148
Downstream Allosteric Modulation of NMDA Receptors by 3-Benzazepine Derivatives.
Ritter N, Disse P, Aymanns I, Mücher L, Schreiber JA, Brenker C, Strünker T, Schepmann D, Budde T, Strutz-Seebohm N, Ametamey SM, Wünsch B, Seebohm G. Ritter N, et al. Among authors: wunsch b. Mol Neurobiol. 2023 Dec;60(12):7238-7252. doi: 10.1007/s12035-023-03526-1. Epub 2023 Aug 5. Mol Neurobiol. 2023. PMID: 37542648 Free PMC article.
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain.
Rossino G, Marra A, Listro R, Peviani M, Poggio E, Curti D, Pellavio G, Laforenza U, Dondio G, Schepmann D, Wünsch B, Bedeschi M, Marino N, Tesei A, Ha HJ, Kim YH, Ann J, Lee J, Linciano P, Di Giacomo M, Rossi D, Collina S. Rossino G, et al. Among authors: wunsch b. Pharmaceuticals (Basel). 2023 Jul 5;16(7):962. doi: 10.3390/ph16070962. Pharmaceuticals (Basel). 2023. PMID: 37513874 Free PMC article.
321 results