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BTK inhibitor-induced defects in human neutrophil effector activity against Aspergillus fumigatus are restored by TNFα.
Vargas-Blanco DA, Hepworth OW, Basham KJ, Simaku P, Crossen AJ, Timmer KD, Hopke A, Brown Harding H, Vandal SR, Jensen KN, Floyd DJ, Reedy JL, Reardon C, Mansour MK, Ward RA, Irimia D, Abramson JS, Vyas JM. Vargas-Blanco DA, et al. Among authors: vyas jm. JCI Insight. 2024 May 7:e176162. doi: 10.1172/jci.insight.176162. Online ahead of print. JCI Insight. 2024. PMID: 38713531 Free article.
Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses.
Brandt M, Cao Z, Krishna C, Reedy JL, Gu X, Dutko RA, Oliver BA, Tusi BK, Park J, Richey L, Segerstolpe Å, Litwiler S, Creasey EA, Carey KL, Vyas JM, Graham DB, Xavier RJ. Brandt M, et al. Among authors: vyas jm. Cell Rep. 2024 Mar 26;43(3):113944. doi: 10.1016/j.celrep.2024.113944. Epub 2024 Mar 13. Cell Rep. 2024. PMID: 38489265 Free PMC article.
SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency.
Li Y, Choudhary MC, Regan J, Boucau J, Nathan A, Speidel T, Liew MY, Edelstein GE, Kawano Y, Uddin R, Deo R, Marino C, Getz MA, Reynolds Z, Barry M, Gilbert RF, Tien D, Sagar S, Vyas TD, Flynn JP, Hammond SP, Novack LA, Choi B, Cernadas M, Wallace ZS, Sparks JA, Vyas JM, Seaman MS, Gaiha GD, Siedner MJ, Barczak AK, Lemieux JE, Li JZ. Li Y, et al. Among authors: vyas jm. Sci Transl Med. 2024 Jan 24;16(731):eadk1599. doi: 10.1126/scitranslmed.adk1599. Epub 2024 Jan 24. Sci Transl Med. 2024. PMID: 38266109 Free PMC article.
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING.
Brown Harding H, Kwaku GN, Reardon CM, Khan NS, Zamith-Miranda D, Zarnowski R, Tam JM, Bohaen CK, Richey L, Mosallanejad K, Crossen AJ, Reedy JL, Ward RA, Vargas-Blanco DA, Basham KJ, Bhattacharyya RP, Nett JE, Mansour MK, van de Veerdonk FL, Kumar V, Kagan JC, Andes DR, Nosanchuk JD, Vyas JM. Brown Harding H, et al. Among authors: vyas jm. Nat Microbiol. 2024 Jan;9(1):95-107. doi: 10.1038/s41564-023-01546-0. Epub 2024 Jan 2. Nat Microbiol. 2024. PMID: 38168615 Free PMC article.
The discovery of hidden guanylate cyclases (GCs) in the Homo sapiens proteome.
Turek I, Freihat L, Vyas J, Wheeler J, Muleya V, Manallack DT, Gehring C, Irving H. Turek I, et al. Among authors: vyas j. Comput Struct Biotechnol J. 2023 Nov 4;21:5523-5529. doi: 10.1016/j.csbj.2023.11.005. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 38022692 Free PMC article.
SARS-CoV-2 Virologic Rebound With Nirmatrelvir-Ritonavir Therapy : An Observational Study.
Edelstein GE, Boucau J, Uddin R, Marino C, Liew MY, Barry M, Choudhary MC, Gilbert RF, Reynolds Z, Li Y, Tien D, Sagar S, Vyas TD, Kawano Y, Sparks JA, Hammond SP, Wallace Z, Vyas JM, Barczak AK, Lemieux JE, Li JZ, Siedner MJ. Edelstein GE, et al. Among authors: vyas jm. Ann Intern Med. 2023 Dec;176(12):1577-1585. doi: 10.7326/M23-1756. Epub 2023 Nov 14. Ann Intern Med. 2023. PMID: 37956428 Free PMC article.
242 results