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Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease.
Drouin-Ouellet J, Legault EM, Nilsson F, Pircs K, Bouquety J, Petit F, Shrigley S, Birtele M, Pereira M, Storm P, Sharma Y, Bruzelius A, Vuono R, Kele M, Stoker TB, Ottosson DR, Falk A, Jakobsson J, Barker RA, Parmar M. Drouin-Ouellet J, et al. Among authors: vuono r. Stem Cell Reports. 2022 Oct 11;17(10):2203-2219. doi: 10.1016/j.stemcr.2022.08.010. Epub 2022 Sep 22. Stem Cell Reports. 2022. PMID: 36150382 Free PMC article.
Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation.
Pircs K, Petri R, Madsen S, Brattås PL, Vuono R, Ottosson DR, St-Amour I, Hersbach BA, Matusiak-Brückner M, Lundh SH, Petersén Å, Déglon N, Hébert SS, Parmar M, Barker RA, Jakobsson J. Pircs K, et al. Among authors: vuono r. Cell Rep. 2018 Aug 7;24(6):1397-1406. doi: 10.1016/j.celrep.2018.07.017. Cell Rep. 2018. PMID: 30089251 Free article.
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease.
Pircs K, Drouin-Ouellet J, Horváth V, Gil J, Rezeli M, Garza R, Grassi DA, Sharma Y, St-Amour I, Harris K, Jönsson ME, Johansson PA, Vuono R, Fazal SV, Stoker T, Hersbach BA, Sharma K, Lagerwall J, Lagerström S, Storm P, Hébert SS, Marko-Varga G, Parmar M, Barker RA, Jakobsson J. Pircs K, et al. Among authors: vuono r. Brain. 2022 Sep 14;145(9):3035-3057. doi: 10.1093/brain/awab473. Brain. 2022. PMID: 34936701 Free PMC article.
REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways.
Drouin-Ouellet J, Lau S, Brattås PL, Rylander Ottosson D, Pircs K, Grassi DA, Collins LM, Vuono R, Andersson Sjöland A, Westergren-Thorsson G, Graff C, Minthon L, Toresson H, Barker RA, Jakobsson J, Parmar M. Drouin-Ouellet J, et al. Among authors: vuono r. EMBO Mol Med. 2017 Aug;9(8):1117-1131. doi: 10.15252/emmm.201607471. EMBO Mol Med. 2017. PMID: 28646119 Free PMC article.
Association Between Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Genetic Variants and Clinical Progression of Huntington's Disease.
Vuono R, Kouli A, Legault EM, Chagnon L, Allinson KS, La Spada A; REGISTRY Investigators of the European Huntington's Disease Network; Biunno I, Barker RA, Drouin-Ouellet J. Vuono R, et al. Mov Disord. 2020 Mar;35(3):401-408. doi: 10.1002/mds.27911. Epub 2019 Nov 14. Mov Disord. 2020. PMID: 31724242 Free PMC article.
Sleep and circadian rhythm regulation in early Parkinson disease.
Breen DP, Vuono R, Nawarathna U, Fisher K, Shneerson JM, Reddy AB, Barker RA. Breen DP, et al. Among authors: vuono r. JAMA Neurol. 2014 May;71(5):589-595. doi: 10.1001/jamaneurol.2014.65. JAMA Neurol. 2014. PMID: 24687146 Free PMC article.
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