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Organoid models of human and mouse ductal pancreatic cancer.
Boj SF, Hwang CI, Baker LA, Chio II, Engle DD, Corbo V, Jager M, Ponz-Sarvise M, Tiriac H, Spector MS, Gracanin A, Oni T, Yu KH, van Boxtel R, Huch M, Rivera KD, Wilson JP, Feigin ME, Öhlund D, Handly-Santana A, Ardito-Abraham CM, Ludwig M, Elyada E, Alagesan B, Biffi G, Yordanov GN, Delcuze B, Creighton B, Wright K, Park Y, Morsink FH, Molenaar IQ, Borel Rinkes IH, Cuppen E, Hao Y, Jin Y, Nijman IJ, Iacobuzio-Donahue C, Leach SD, Pappin DJ, Hammell M, Klimstra DS, Basturk O, Hruban RH, Offerhaus GJ, Vries RG, Clevers H, Tuveson DA. Boj SF, et al. Among authors: vries rg. Cell. 2015 Jan 15;160(1-2):324-38. doi: 10.1016/j.cell.2014.12.021. Epub 2014 Dec 31. Cell. 2015. PMID: 25557080 Free PMC article.
The kinase TNIK is an essential activator of Wnt target genes.
Mahmoudi T, Li VS, Ng SS, Taouatas N, Vries RG, Mohammed S, Heck AJ, Clevers H. Mahmoudi T, et al. Among authors: vries rg. EMBO J. 2009 Nov 4;28(21):3329-40. doi: 10.1038/emboj.2009.285. Epub 2009 Oct 8. EMBO J. 2009. PMID: 19816403 Free PMC article.
Stem cells and cancer of the stomach and intestine.
Vries RG, Huch M, Clevers H. Vries RG, et al. Mol Oncol. 2010 Oct;4(5):373-84. doi: 10.1016/j.molonc.2010.05.001. Epub 2010 Jun 8. Mol Oncol. 2010. PMID: 20598659 Free PMC article. Review.
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.
Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H. Sato T, et al. Among authors: vries rg. Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28. Nature. 2011. PMID: 21113151 Free PMC article.
Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target.
Van Houdt WJ, Emmink BL, Pham TV, Piersma SR, Verheem A, Vries RG, Fratantoni SA, Pronk A, Clevers H, Borel Rinkes IH, Jimenez CR, Kranenburg O. Van Houdt WJ, et al. Among authors: vries rg. Mol Cell Proteomics. 2011 Dec;10(12):M111.011353. doi: 10.1074/mcp.M111.011353. Epub 2011 Jul 25. Mol Cell Proteomics. 2011. PMID: 21788403 Free PMC article.
107 results