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From microbiome composition to functional engineering, one step at a time.
Burz SD, Causevic S, Dal Co A, Dmitrijeva M, Engel P, Garrido-Sanz D, Greub G, Hapfelmeier S, Hardt W-D, Hatzimanikatis V, Heiman CM, Herzog MK-M, Hockenberry A, Keel C, Keppler A, Lee S-J, Luneau J, Malfertheiner L, Mitri S, Ngyuen B, Oftadeh O, Pacheco AR, Peaudecerf F, Resch G, Ruscheweyh H-J, Sahin A, Sanders IR, Slack E, Sunagawa S, Tackmann J, Tecon R, Ugolini GS, Vacheron J, van der Meer JR, Vayena E, Vonaesch P, Vorholt JA. Burz SD, et al. Among authors: vorholt ja. Microbiol Mol Biol Rev. 2023 Dec 20;87(4):e0006323. doi: 10.1128/mmbr.00063-23. Epub 2023 Nov 10. Microbiol Mol Biol Rev. 2023. PMID: 37947420 Free PMC article. Review.
Import of Aspartate and Malate by DcuABC Drives H2/Fumarate Respiration to Promote Initial Salmonella Gut-Lumen Colonization in Mice.
Nguyen BD, Cuenca V M, Hartl J, Gül E, Bauer R, Meile S, Rüthi J, Margot C, Heeb L, Besser F, Escriva PP, Fetz C, Furter M, Laganenka L, Keller P, Fuchs L, Christen M, Porwollik S, McClelland M, Vorholt JA, Sauer U, Sunagawa S, Christen B, Hardt WD. Nguyen BD, et al. Among authors: vorholt ja. Cell Host Microbe. 2020 Jun 10;27(6):922-936.e6. doi: 10.1016/j.chom.2020.04.013. Epub 2020 May 15. Cell Host Microbe. 2020. PMID: 32416061 Free PMC article.
A general non-self response as part of plant immunity.
Maier BA, Kiefer P, Field CM, Hemmerle L, Bortfeld-Miller M, Emmenegger B, Schäfer M, Pfeilmeier S, Sunagawa S, Vogel CM, Vorholt JA. Maier BA, et al. Among authors: vorholt ja. Nat Plants. 2021 May;7(5):696-705. doi: 10.1038/s41477-021-00913-1. Epub 2021 May 17. Nat Plants. 2021. PMID: 34007033 Free PMC article.
Metabolic interaction models recapitulate leaf microbiota ecology.
Schäfer M, Pacheco AR, Künzler R, Bortfeld-Miller M, Field CM, Vayena E, Hatzimanikatis V, Vorholt JA. Schäfer M, et al. Among authors: vorholt ja. Science. 2023 Jul 7;381(6653):eadf5121. doi: 10.1126/science.adf5121. Epub 2023 Jul 7. Science. 2023. PMID: 37410834
Direct Salmonella injection into enteroid cells allows the study of host-pathogen interactions in the cytosol with high spatiotemporal resolution.
Ernst C, Andreassen PR, Giger GH, Nguyen BD, Gäbelein CG, Guillaume-Gentil O, Fattinger SA, Sellin ME, Hardt WD, Vorholt JA. Ernst C, et al. Among authors: vorholt ja. PLoS Biol. 2024 Apr 29;22(4):e3002597. doi: 10.1371/journal.pbio.3002597. eCollection 2024 Apr. PLoS Biol. 2024. PMID: 38684033 Free PMC article.
191 results