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Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome.
Shen C, Li R, Negro R, Cheng J, Vora SM, Fu TM, Wang A, He K, Andreeva L, Gao P, Tian Z, Flavell RA, Zhu S, Wu H. Shen C, et al. Among authors: vora sm. Cell. 2021 Nov 11;184(23):5759-5774.e20. doi: 10.1016/j.cell.2021.09.032. Epub 2021 Oct 21. Cell. 2021. PMID: 34678144 Free PMC article.
Structures and functions of the inflammasome engine.
Wang L, Sharif H, Vora SM, Zheng Y, Wu H. Wang L, et al. Among authors: vora sm. J Allergy Clin Immunol. 2021 Jun;147(6):2021-2029. doi: 10.1016/j.jaci.2021.04.018. J Allergy Clin Immunol. 2021. PMID: 34092352 Free PMC article. Review.
Inflammasome activation at the crux of severe COVID-19.
Vora SM, Lieberman J, Wu H. Vora SM, et al. Nat Rev Immunol. 2021 Nov;21(11):694-703. doi: 10.1038/s41577-021-00588-x. Epub 2021 Aug 9. Nat Rev Immunol. 2021. PMID: 34373622 Free PMC article. Review.
Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Xia S, Zhang Z, Magupalli VG, Pablo JL, Dong Y, Vora SM, Wang L, Fu TM, Jacobson MP, Greka A, Lieberman J, Ruan J, Wu H. Xia S, et al. Among authors: vora sm. Nature. 2021 May;593(7860):607-611. doi: 10.1038/s41586-021-03478-3. Epub 2021 Apr 21. Nature. 2021. PMID: 33883744 Free PMC article.
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.
Junqueira C, Crespo Â, Ranjbar S, de Lacerda LB, Lewandrowski M, Ingber J, Parry B, Ravid S, Clark S, Schrimpf MR, Ho F, Beakes C, Margolin J, Russell N, Kays K, Boucau J, Das Adhikari U, Vora SM, Leger V, Gehrke L, Henderson LA, Janssen E, Kwon D, Sander C, Abraham J, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Filbin MR, Lieberman J. Junqueira C, et al. Among authors: vora sm. Nature. 2022 Jun;606(7914):576-584. doi: 10.1038/s41586-022-04702-4. Epub 2022 Apr 6. Nature. 2022. PMID: 35385861 Free PMC article.
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