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Platelet-derived HMGB1 is a critical mediator of thrombosis.
Vogel S, Bodenstein R, Chen Q, Feil S, Feil R, Rheinlaender J, Schäffer TE, Bohn E, Frick JS, Borst O, Münzer P, Walker B, Markel J, Csanyi G, Pagano PJ, Loughran P, Jessup ME, Watkins SC, Bullock GC, Sperry JL, Zuckerbraun BS, Billiar TR, Lotze MT, Gawaz M, Neal MD. Vogel S, et al. J Clin Invest. 2015 Dec;125(12):4638-54. doi: 10.1172/JCI81660. Epub 2015 Nov 9. J Clin Invest. 2015. PMID: 26551681 Free PMC article.
Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
von Ungern-Sternberg SNI, Vogel S, Walker-Allgaier B, Geue S, Maurer A, Wild AM, Münzer P, Chatterjee M, Heinzmann D, Kremmer E, Borst O, Loughran P, Zernecke A, Neal MD, Billiar TR, Gawaz M, Seizer P. von Ungern-Sternberg SNI, et al. Among authors: vogel s. Thromb Haemost. 2017 Nov;117(11):2063-2078. doi: 10.1160/TH17-01-0067. Epub 2017 Nov 30. Thromb Haemost. 2017. PMID: 28981554 Free PMC article.
Sphingosine kinase 1 (Sphk1) negatively regulates platelet activation and thrombus formation.
Münzer P, Schmid E, Walker B, Fotinos A, Chatterjee M, Rath D, Vogel S, Hoffmann SM, Metzger K, Seizer P, Geisler T, Gawaz M, Borst O, Lang F. Münzer P, et al. Among authors: vogel s. Am J Physiol Cell Physiol. 2014 Nov 15;307(10):C920-7. doi: 10.1152/ajpcell.00029.2014. Epub 2014 Sep 17. Am J Physiol Cell Physiol. 2014. PMID: 25231106 Free PMC article.
Activated platelets interfere with recruitment of mesenchymal stem cells to apoptotic cardiac cells via high mobility group box 1/Toll-like receptor 4-mediated down-regulation of hepatocyte growth factor receptor MET.
Vogel S, Chatterjee M, Metzger K, Borst O, Geisler T, Seizer P, Müller I, Mack A, Schumann S, Bühring HJ, Lang F, Sorg RV, Langer H, Gawaz M. Vogel S, et al. J Biol Chem. 2014 Apr 18;289(16):11068-11082. doi: 10.1074/jbc.M113.530287. Epub 2014 Feb 24. J Biol Chem. 2014. PMID: 24567328 Free PMC article.
1,435 results