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Extracellular matrix-based cancer targeting.
Karamanos NK, Piperigkou Z, Passi A, Götte M, Rousselle P, Vlodavsky I. Karamanos NK, et al. Among authors: vlodavsky i. Trends Mol Med. 2021 Oct;27(10):1000-1013. doi: 10.1016/j.molmed.2021.07.009. Epub 2021 Aug 10. Trends Mol Med. 2021. PMID: 34389240 Review.
Translocation of active heparanase to cell surface regulates degradation of extracellular matrix heparan sulfate upon transmigration of mature monocyte-derived dendritic cells.
Benhamron S, Nechushtan H, Verbovetski I, Krispin A, Abboud-Jarrous G, Zcharia E, Edovitsky E, Nahari E, Peretz T, Vlodavsky I, Mevorach D. Benhamron S, et al. Among authors: vlodavsky i. J Immunol. 2006 Jun 1;176(11):6417-24. doi: 10.4049/jimmunol.176.11.6417. J Immunol. 2006. PMID: 16709798
Heparanase: busy at the cell surface.
Fux L, Ilan N, Sanderson RD, Vlodavsky I. Fux L, et al. Among authors: vlodavsky i. Trends Biochem Sci. 2009 Oct;34(10):511-9. doi: 10.1016/j.tibs.2009.06.005. Epub 2009 Sep 3. Trends Biochem Sci. 2009. PMID: 19733083 Free PMC article. Review.
Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior.
Bandari SK, Purushothaman A, Ramani VC, Brinkley GJ, Chandrashekar DS, Varambally S, Mobley JA, Zhang Y, Brown EE, Vlodavsky I, Sanderson RD. Bandari SK, et al. Among authors: vlodavsky i. Matrix Biol. 2018 Jan;65:104-118. doi: 10.1016/j.matbio.2017.09.001. Epub 2017 Sep 6. Matrix Biol. 2018. PMID: 28888912 Free PMC article.
Nuclear localization of heparanase 2 (Hpa2) attenuates breast carcinoma growth and metastasis.
Hilwi M, Shulman K, Naroditsky I, Feld S, Gross-Cohen M, Boyango I, Soboh S, Vornicova O, Farhoud M, Singh P, Bar-Sela G, Goldberg H, Götte M, Sharrocks AD, Li Y, Sanderson RD, Ilan N, Vlodavsky I. Hilwi M, et al. Among authors: vlodavsky i. Cell Death Dis. 2024 Mar 22;15(3):232. doi: 10.1038/s41419-024-06596-8. Cell Death Dis. 2024. PMID: 38519456 Free PMC article.
518 results