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Replacement of Nitrite in Meat Products by Natural Bioactive Compounds Results in Reduced Exposure to N-Nitroso Compounds: The PHYTOME Project.
van Breda SG, Mathijs K, Pieters HJ, Sági-Kiss V, Kuhnle GG, Georgiadis P, Saccani G, Parolari G, Virgili R, Sinha R, Hemke G, Hung Y, Verbeke W, Masclee AA, Vleugels-Simon CB, van Bodegraven AA, de Kok TM; PHYTOME consortium. van Breda SG, et al. Among authors: vleugels simon cb. Mol Nutr Food Res. 2021 Oct;65(20):e2001214. doi: 10.1002/mnfr.202001214. Epub 2021 Aug 27. Mol Nutr Food Res. 2021. PMID: 34382747 Free PMC article.
N-nitroso compound exposure-associated transcriptomic profiles are indicative of an increased risk for colorectal cancer.
Hebels DG, Sveje KM, de Kok MC, van Herwijnen MH, Kuhnle GG, Engels LG, Vleugels-Simon CB, Mares WG, Pierik M, Masclee AA, Kleinjans JC, de Kok TM. Hebels DG, et al. Among authors: vleugels simon cb. Cancer Lett. 2011 Oct 1;309(1):1-10. doi: 10.1016/j.canlet.2011.05.007. Epub 2011 Jun 12. Cancer Lett. 2011. PMID: 21669488 Free article.
Red meat intake-induced increases in fecal water genotoxicity correlate with pro-carcinogenic gene expression changes in the human colon.
Hebels DG, Sveje KM, de Kok MC, van Herwijnen MH, Kuhnle GG, Engels LG, Vleugels-Simon CB, Mares WG, Pierik M, Masclee AA, Kleinjans JC, de Kok TM. Hebels DG, et al. Among authors: vleugels simon cb. Food Chem Toxicol. 2012 Feb;50(2):95-103. doi: 10.1016/j.fct.2011.10.038. Epub 2011 Oct 14. Food Chem Toxicol. 2012. PMID: 22019696