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Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism.
van Welsem T, Korthout T, Ekkebus R, Morais D, Molenaar TM, van Harten K, Poramba-Liyanage DW, Sun SM, Lenstra TL, Srivas R, Ideker T, Holstege FCP, van Attikum H, El Oualid F, Ovaa H, Stulemeijer IJE, Vlaming H, van Leeuwen F. van Welsem T, et al. Among authors: vlaming h. Nucleic Acids Res. 2018 Nov 30;46(21):11251-11261. doi: 10.1093/nar/gky801. Nucleic Acids Res. 2018. PMID: 30203048 Free PMC article.
Crosstalk between aging and the epigenome.
Vlaming H, van Leeuwen F. Vlaming H, et al. Epigenomics. 2012 Feb;4(1):5-7. doi: 10.2217/epi.11.113. Epigenomics. 2012. PMID: 22332652 No abstract available.
Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.
Hustedt N, Seeber A, Sack R, Tsai-Pflugfelder M, Bhullar B, Vlaming H, van Leeuwen F, Guénolé A, van Attikum H, Srivas R, Ideker T, Shimada K, Gasser SM. Hustedt N, et al. Among authors: vlaming h. Mol Cell. 2015 Jan 22;57(2):273-89. doi: 10.1016/j.molcel.2014.11.016. Epub 2014 Dec 18. Mol Cell. 2015. PMID: 25533186 Free PMC article.
Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.
Vlaming H, McLean CM, Korthout T, Alemdehy MF, Hendriks S, Lancini C, Palit S, Klarenbeek S, Kwesi-Maliepaard EM, Molenaar TM, Hoekman L, Schmidlin TT, Altelaar AM, van Welsem T, Dannenberg JH, Jacobs H, van Leeuwen F. Vlaming H, et al. EMBO J. 2019 Jul 15;38(14):e101564. doi: 10.15252/embj.2019101564. Epub 2019 Jun 17. EMBO J. 2019. PMID: 31304633 Free PMC article.
The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells.
Kwesi-Maliepaard EM, Aslam MA, Alemdehy MF, van den Brand T, McLean C, Vlaming H, van Welsem T, Korthout T, Lancini C, Hendriks S, Ahrends T, van Dinther D, den Haan JMM, Borst J, de Wit E, van Leeuwen F, Jacobs H. Kwesi-Maliepaard EM, et al. Among authors: vlaming h. Proc Natl Acad Sci U S A. 2020 Aug 25;117(34):20706-20716. doi: 10.1073/pnas.1920372117. Epub 2020 Aug 6. Proc Natl Acad Sci U S A. 2020. PMID: 32764145 Free PMC article.
15 results