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RICTOR/mTORC2 downregulation in BRAFV600E melanoma cells promotes resistance to BRAF/MEK inhibition.
Ponzone L, Audrito V, Landi C, Moiso E, Levra Levron C, Ferrua S, Savino A, Vitale N, Gasparrini M, Avalle L, Vantaggiato L, Shaba E, Tassone B, Saoncella S, Orso F, Viavattene D, Marina E, Fiorilla I, Burrone G, Abili Y, Altruda F, Bini L, Deaglio S, Defilippi P, Menga A, Poli V, Porporato PE, Provero P, Raffaelli N, Riganti C, Taverna D, Cavallo F, Calautti E. Ponzone L, et al. Among authors: vitale n. Mol Cancer. 2024 May 16;23(1):105. doi: 10.1186/s12943-024-02010-1. Mol Cancer. 2024. PMID: 38755661
Restoring cellular copper homeostasis in Alzheimer disease: a novel peptide shuttle is internalized by an ATP-dependent endocytosis pathway involving Rab5- and Rab14-endosomes.
Okafor M, Champomier O, Raibaut L, Ozkan S, El Kholti N, Ory S, Chasserot-Golaz S, Gasman S, Hureau C, Faller P, Vitale N. Okafor M, et al. Among authors: vitale n. Front Mol Biosci. 2024 Apr 5;11:1355963. doi: 10.3389/fmolb.2024.1355963. eCollection 2024. Front Mol Biosci. 2024. PMID: 38645276 Free PMC article.
The DDHD2-STXBP1 interaction mediates long-term memory via generation of saturated free fatty acids.
Akefe IO, Saber SH, Matthews B, Venkatesh BG, Gormal RS, Blackmore DG, Alexander S, Sieriecki E, Gambin Y, Bertran-Gonzalez J, Vitale N, Humeau Y, Gaudin A, Ellis SA, Michaels AA, Xue M, Cravatt B, Joensuu M, Wallis TP, Meunier FA. Akefe IO, et al. Among authors: vitale n. EMBO J. 2024 Feb;43(4):533-567. doi: 10.1038/s44318-024-00030-7. Epub 2024 Feb 5. EMBO J. 2024. PMID: 38316990 Free PMC article.
321 results