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Noncoding regions are the main source of targetable tumor-specific antigens.
Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, Haddad E, Lemieux S, Thibault P, Perreault C. Laumont CM, et al. Among authors: vincent k. Sci Transl Med. 2018 Dec 5;10(470):eaau5516. doi: 10.1126/scitranslmed.aau5516. Sci Transl Med. 2018. PMID: 30518613
Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules.
de Verteuil D, Muratore-Schroeder TL, Granados DP, Fortier MH, Hardy MP, Bramoullé A, Caron E, Vincent K, Mader S, Lemieux S, Thibault P, Perreault C. de Verteuil D, et al. Among authors: vincent k. Mol Cell Proteomics. 2010 Sep;9(9):2034-47. doi: 10.1074/mcp.M900566-MCP200. Epub 2010 May 19. Mol Cell Proteomics. 2010. PMID: 20484733 Free PMC article.
Next-generation leukemia immunotherapy.
Vincent K, Roy DC, Perreault C. Vincent K, et al. Blood. 2011 Sep 15;118(11):2951-9. doi: 10.1182/blood-2011-04-350868. Epub 2011 Jul 6. Blood. 2011. PMID: 21734234 Free article. Review.
Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer.
Zhao Q, Laverdure JP, Lanoix J, Durette C, Côté C, Bonneil É, Laumont CM, Gendron P, Vincent K, Courcelles M, Lemieux S, Millar DG, Ohashi PS, Thibault P, Perreault C. Zhao Q, et al. Among authors: vincent k. Cancer Immunol Res. 2020 Apr;8(4):544-555. doi: 10.1158/2326-6066.CIR-19-0541. Epub 2020 Feb 11. Cancer Immunol Res. 2020. PMID: 32047025
MAPDP: A Cloud-Based Computational Platform for Immunopeptidomics Analyses.
Courcelles M, Durette C, Daouda T, Laverdure JP, Vincent K, Lemieux S, Perreault C, Thibault P. Courcelles M, et al. Among authors: vincent k. J Proteome Res. 2020 Apr 3;19(4):1873-1881. doi: 10.1021/acs.jproteome.9b00859. Epub 2020 Mar 13. J Proteome Res. 2020. PMID: 32108478
676 results