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Page 1
Budesonide Analogues Preserve Stem Cell Pluripotency and Delay 3D Gastruloid Development.
Amoroso F, Ibello E, Saracino F, Cermola F, Ponticelli G, Scalera E, Ricci F, Villetti G, Cobellis G, Minchiotti G, Patriarca EJ, De Cesare D, D'Aniello C. Amoroso F, et al. Among authors: villetti g. Pharmaceutics. 2023 Jul 6;15(7):1897. doi: 10.3390/pharmaceutics15071897. Pharmaceutics. 2023. PMID: 37514083 Free PMC article.
A mouse model of progressive lung fibrosis with cutaneous involvement induced by a combination of oropharyngeal and osmotic minipump bleomycin delivery.
Grandi A, Ferrini E, Zoboli M, Buseghin D, Pennati F, Khalajzeyqami Z, Ciccimarra R, Villetti G, Stellari FF. Grandi A, et al. Among authors: villetti g. Am J Physiol Lung Cell Mol Physiol. 2024 Apr 23. doi: 10.1152/ajplung.00408.2023. Online ahead of print. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 38651940 Free article.
CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.
Martucci C, Allen AD, Moretto N, Bagnacani V, Fioni A, Patacchini R, Civelli M, Villetti G, Facchinetti F. Martucci C, et al. Among authors: villetti g. Front Pharmacol. 2024 Mar 14;15:1343941. doi: 10.3389/fphar.2024.1343941. eCollection 2024. Front Pharmacol. 2024. PMID: 38549671 Free PMC article.
Time-course transcriptome analysis of a double challenge bleomycin-induced lung fibrosis rat model uncovers ECM homoeostasis-related translationally relevant genes.
Bonatti M, Pitozzi V, Caruso P, Pontis S, Pittelli MG, Frati C, Mangiaracina C, Lagrasta CAM, Quaini F, Cantarella S, Ottonello S, Villetti G, Civelli M, Montanini B, Trevisani M. Bonatti M, et al. Among authors: villetti g. BMJ Open Respir Res. 2023 Sep;10(1):e001476. doi: 10.1136/bmjresp-2022-001476. BMJ Open Respir Res. 2023. PMID: 37730279 Free PMC article.
Optimization of M3 Antagonist-PDE4 Inhibitor (MAPI) Dual Pharmacology Molecules for the Treatment of COPD.
Rizzi A, Amari G, Pivetti F, Delcanale M, Amadei F, Pappani A, Fornasari L, Villetti G, Marchini G, Pisano AR, Pitozzi V, Pittelli MG, Trevisani M, Salvadori M, Cenacchi V, Fioni A, Puccini P, Civelli M, Patacchini R, Baker-Glenn C, Van de Poël H, Blackaby W, Nash K, Armani E. Rizzi A, et al. Among authors: villetti g. J Med Chem. 2023 Aug 24;66(16):11476-11497. doi: 10.1021/acs.jmedchem.3c01012. Epub 2023 Aug 10. J Med Chem. 2023. PMID: 37561958
Discovery of a Potent, Selective, and Orally Bioavailable Tool Compound for Probing the Role of Lysophosphatidic Acid Type 2 Receptor Antagonists in Fibrotic Disorders.
Armani E, Rizzi A, Iotti N, Saccani F, Di Lascia MR, Tigli L, Pappani A, Marchini G, Murgo A, Capelli AM, Delcanale M, Puccini P, Villetti G, Civelli M, Beato C, Giuliani M, Mundi C, Murarolli F, Pagano M, Raveglia LF, Remelli R, Amari G. Armani E, et al. Among authors: villetti g. J Med Chem. 2023 Apr 27;66(8):5622-5656. doi: 10.1021/acs.jmedchem.2c02087. Epub 2023 Apr 5. J Med Chem. 2023. PMID: 37017110
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