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Page 1
Elevated cholesterol in ATAD3 mutants is a compensatory mechanism that leads to membrane cholesterol aggregation.
Muñoz-Oreja M, Sandoval A, Bruland O, Perez-Rodriguez D, Fernandez-Pelayo U, de Arbina AL, Villar-Fernandez M, Hernández-Eguiazu H, Hernández I, Park Y, Goicoechea L, Pascual-Frías N, Garcia-Ruiz C, Fernandez-Checa J, Martí-Carrera I, Gil-Bea FJ, Hasan MT, Gegg ME, Bredrup C, Knappskog PM, Gereñu-Lopetegui G, Varhaug KN, Bindoff LA, Spinazzola A, Yoon WH, Holt IJ. Muñoz-Oreja M, et al. Among authors: villar fernandez m. Brain. 2024 May 3;147(5):1899-1913. doi: 10.1093/brain/awae018. Brain. 2024. PMID: 38242545 Free PMC article.
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG. Ghallab A, et al. Among authors: villar fernandez m. J Hepatol. 2024 Feb;80(2):268-281. doi: 10.1016/j.jhep.2023.10.035. Epub 2023 Nov 7. J Hepatol. 2024. PMID: 37939855 Free PMC article.
Basic concepts of mixture toxicity and relevance for risk evaluation and regulation.
Bloch D, Diel P, Epe B, Hellwig M, Lampen A, Mally A, Marko D, Villar Fernández MA, Guth S, Roth A, Marchan R, Ghallab A, Cadenas C, Nell P, Vartak N, van Thriel C, Luch A, Schmeisser S, Herzler M, Landsiedel R, Leist M, Marx-Stoelting P, Tralau T, Hengstler JG. Bloch D, et al. Among authors: villar fernandez ma. Arch Toxicol. 2023 Nov;97(11):3005-3017. doi: 10.1007/s00204-023-03565-6. Epub 2023 Aug 24. Arch Toxicol. 2023. PMID: 37615677 Free PMC article. Review.
2 deoxy-D-glucose augments the mitochondrial respiratory chain in heart.
Aiestaran-Zelaia I, Sánchez-Guisado MJ, Villar-Fernandez M, Azkargorta M, Fadon-Padilla L, Fernandez-Pelayo U, Perez-Rodriguez D, Ramos-Cabrer P, Spinazzola A, Elortza F, Ruíz-Cabello J, Holt IJ. Aiestaran-Zelaia I, et al. Among authors: villar fernandez m. Sci Rep. 2022 Apr 27;12(1):6890. doi: 10.1038/s41598-022-10168-1. Sci Rep. 2022. PMID: 35478201 Free PMC article.
2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA.
Pantic B, Ives D, Mennuni M, Perez-Rodriguez D, Fernandez-Pelayo U, Lopez de Arbina A, Muñoz-Oreja M, Villar-Fernandez M, Dang TJ, Vergani L, Johnston IG, Pitceathly RDS, McFarland R, Hanna MG, Taylor RW, Holt IJ, Spinazzola A. Pantic B, et al. Among authors: villar fernandez m. Nat Commun. 2021 Dec 6;12(1):6997. doi: 10.1038/s41467-021-26829-0. Nat Commun. 2021. PMID: 34873176 Free PMC article.
Predictive variables of sustained virological response after early discontinuation of triple therapy with telaprevir for genotype-1 HCV infection.
Acero Fernández D, Morillas Cunill R, Ferri Iglesias MJ, Torras Collell X, Vergara Gómez M, Zaragoza Velasco N, López Nuñez C, Forné Bardera M, Delgado Gómez M, Barenys Lacha M, Torres Salinas M, Villar Fernández M, Durández Lázaro R, Mariño Mendez Z. Acero Fernández D, et al. Among authors: villar fernandez m. Gastroenterol Hepatol. 2016 Jun-Jul;39(6):377-84. doi: 10.1016/j.gastrohep.2015.10.005. Epub 2015 Nov 21. Gastroenterol Hepatol. 2016. PMID: 26614733
Outlook for Tissue Engineering of the Tympanic Membrane.
Villar-Fernandez MA, Lopez-Escamez JA. Villar-Fernandez MA, et al. Audiol Res. 2015 Jan 23;5(1):117. doi: 10.4081/audiores.2015.117. eCollection 2015 Jan 21. Audiol Res. 2015. PMID: 26557361 Free PMC article.