Vile RG - Search Results

1

Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice.

Evgin L, Kottke T, Tonne J, Thompson J, Huff AL, van Vloten J, Moore M, Michael J, Driscoll C, Pulido J, Swanson E, Kennedy R, Coffey M, Loghmani H, Sanchez-Perez L, Olivier G, Harrington K, Pandha H, Melcher A, Diaz RM, Vile RG. Evgin L, et al. Among authors: vile rg. Sci Transl Med. 2022 Apr 13;14(640):eabn2231. doi: 10.1126/scitranslmed.abn2231. Epub 2022 Apr 13. Sci Transl Med. 2022. PMID: 35417192 Free PMC article.

2

Targeted gene therapy for cancer: herpes simplex virus thymidine kinase gene-mediated cell killing leads to anti-tumour immunity that can be augmented by co-expression of cytokines in the tumour cells.

Vile RG, Diaz RM, Castleden S, Chong H. Vile RG, et al. Biochem Soc Trans. 1997 May;25(2):717-22. doi: 10.1042/bst0250717. Biochem Soc Trans. 1997. PMID: 9191190 Review. No abstract available.

3

Euro targeting in Leiden: the fourth meeting of the EWGT, University of Leiden, 14-17 November 1996.

Diaz RM, Vile R. Diaz RM, et al. Gene Ther. 1997 Jun;4(6):501-3. doi: 10.1038/sj.gt.3300445. Gene Ther. 1997. PMID: 9231064 No abstract available.

4

A family of bicistronic vectors to enhance both local and systemic antitumor effects of HSVtk or cytokine expression in a murine melanoma model.

Castleden SA, Chong H, Garcia-Ribas I, Melcher AA, Hutchinson G, Roberts B, Hart IR, Vile RG. Castleden SA, et al. Among authors: vile rg. Hum Gene Ther. 1997 Nov 20;8(17):2087-102. doi: 10.1089/hum.1997.8.17-2087. Hum Gene Ther. 1997. PMID: 9414257

5

Exchange of viral promoter/enhancer elements with heterologous regulatory sequences generates targeted hybrid long terminal repeat vectors for gene therapy of melanoma.

Diaz RM, Eisen T, Hart IR, Vile RG. Diaz RM, et al. Among authors: vile rg. J Virol. 1998 Jan;72(1):789-95. doi: 10.1128/JVI.72.1.789-795.1998. J Virol. 1998. PMID: 9420288 Free PMC article.

6

Genetic prodrug activation therapy.

Martin LA, Vile R, Lemoine NR, Sikora K, Pandha HS. Martin LA, et al. Lancet. 1997 Dec 20-27;350(9094):1793-4. doi: 10.1016/s0140-6736(05)63633-1. Lancet. 1997. PMID: 9428248 No abstract available.

7

Gene therapy for cancer--managing expectations.

Melcher AA, Garcia-Ribas I, Vile RG. Melcher AA, et al. Among authors: vile rg. BMJ. 1997 Dec 13;315(7122):1604-7. doi: 10.1136/bmj.315.7122.1604. BMJ. 1997. PMID: 9437283 Free PMC article. Review. No abstract available.

8

Strategies for achieving multiple layers of selectivity in gene therapy.

Vile RG, Sunassee K, Diaz RM. Vile RG, et al. Mol Med Today. 1998 Feb;4(2):84-92. doi: 10.1016/S1357-4310(97)01157-X. Mol Med Today. 1998. PMID: 9547795 Review.

9

Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression.

Melcher A, Todryk S, Hardwick N, Ford M, Jacobson M, Vile RG. Melcher A, et al. Among authors: vile rg. Nat Med. 1998 May;4(5):581-7. doi: 10.1038/nm0598-581. Nat Med. 1998. PMID: 9585232

10

Can immunotherapy by gene transfer tip the balance against colorectal cancer?

Todryk SM, Chong H, Vile RG, Pandha H, Lemoine NR. Todryk SM, et al. Among authors: vile rg. Gut. 1998 Oct;43(4):445-9. doi: 10.1136/gut.43.4.445. Gut. 1998. PMID: 9824562 Free PMC article.

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