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The impact of sex on gene expression across human tissues.
Oliva M, Muñoz-Aguirre M, Kim-Hellmuth S, Wucher V, Gewirtz ADH, Cotter DJ, Parsana P, Kasela S, Balliu B, Viñuela A, Castel SE, Mohammadi P, Aguet F, Zou Y, Khramtsova EA, Skol AD, Garrido-Martín D, Reverter F, Brown A, Evans P, Gamazon ER, Payne A, Bonazzola R, Barbeira AN, Hamel AR, Martinez-Perez A, Soria JM; GTEx Consortium; Pierce BL, Stephens M, Eskin E, Dermitzakis ET, Segrè AV, Im HK, Engelhardt BE, Ardlie KG, Montgomery SB, Battle AJ, Lappalainen T, Guigó R, Stranger BE. Oliva M, et al. Among authors: vinuela a. Science. 2020 Sep 11;369(6509):eaba3066. doi: 10.1126/science.aba3066. Science. 2020. PMID: 32913072 Free PMC article.
Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation.
Tsaprouni LG, Yang TP, Bell J, Dick KJ, Kanoni S, Nisbet J, Viñuela A, Grundberg E, Nelson CP, Meduri E, Buil A, Cambien F, Hengstenberg C, Erdmann J, Schunkert H, Goodall AH, Ouwehand WH, Dermitzakis E, Spector TD, Samani NJ, Deloukas P. Tsaprouni LG, et al. Among authors: vinuela a. Epigenetics. 2014 Oct;9(10):1382-96. doi: 10.4161/15592294.2014.969637. Epigenetics. 2014. PMID: 25424692 Free PMC article.
Adiposity-Dependent Regulatory Effects on Multi-tissue Transcriptomes.
Glastonbury CA, Viñuela A, Buil A, Halldorsson GH, Thorleifsson G, Helgason H, Thorsteinsdottir U, Stefansson K, Dermitzakis ET, Spector TD, Small KS. Glastonbury CA, et al. Among authors: vinuela a. Am J Hum Genet. 2016 Sep 1;99(3):567-579. doi: 10.1016/j.ajhg.2016.07.001. Am J Hum Genet. 2016. PMID: 27588447 Free PMC article.
Time-dependent genetic effects on gene expression implicate aging processes.
Bryois J, Buil A, Ferreira PG, Panousis NI, Brown AA, Viñuela A, Planchon A, Bielser D, Small K, Spector T, Dermitzakis ET. Bryois J, et al. Among authors: vinuela a. Genome Res. 2017 Apr;27(4):545-552. doi: 10.1101/gr.207688.116. Epub 2017 Mar 16. Genome Res. 2017. PMID: 28302734 Free PMC article.
133 results