Vetter I - Search Results

1

Improving the Gastrointestinal Stability of Linaclotide.

Braga Emidio N, Tran HNT, Andersson A, Dawson PE, Albericio F, Vetter I, Muttenthaler M. Braga Emidio N, et al. Among authors: vetter i. J Med Chem. 2021 Jun 24;64(12):8384-8390. doi: 10.1021/acs.jmedchem.1c00380. Epub 2021 May 12. J Med Chem. 2021. PMID: 33979161 Free PMC article.

2

Therapeutic potential of cone snail venom peptides (conopeptides).

Vetter I, Lewis RJ. Vetter I, et al. Curr Top Med Chem. 2012;12(14):1546-52. doi: 10.2174/156802612802652457. Curr Top Med Chem. 2012. PMID: 22827523 Review.

3

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain.

de Araujo AD, Mobli M, Castro J, Harrington AM, Vetter I, Dekan Z, Muttenthaler M, Wan J, Lewis RJ, King GF, Brierley SM, Alewood PF. de Araujo AD, et al. Among authors: vetter i. Nat Commun. 2014;5:3165. doi: 10.1038/ncomms4165. Nat Commun. 2014. PMID: 24476666 Free article.

4

Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca²⁺ entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assay.

Azimi I, Flanagan JU, Stevenson RJ, Inserra M, Vetter I, Monteith GR, Denny WA. Azimi I, et al. Among authors: vetter i. Bioorg Med Chem. 2017 Jan 1;25(1):440-449. doi: 10.1016/j.bmc.2016.11.007. Epub 2016 Nov 7. Bioorg Med Chem. 2017. PMID: 27856238

5

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species.

Muttenthaler M, Andersson Å, Vetter I, Menon R, Busnelli M, Ragnarsson L, Bergmayr C, Arrowsmith S, Deuis JR, Chiu HS, Palpant NJ, O'Brien M, Smith TJ, Wray S, Neumann ID, Gruber CW, Lewis RJ, Alewood PF. Muttenthaler M, et al. Among authors: vetter i. Sci Signal. 2017 Dec 5;10(508):eaan3398. doi: 10.1126/scisignal.aan3398. Sci Signal. 2017. PMID: 29208680 Free PMC article.

6

The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human Na_V1.6.

Israel MR, Thongyoo P, Deuis JR, Craik DJ, Vetter I, Durek T. Israel MR, et al. Among authors: vetter i. J Med Chem. 2018 Feb 22;61(4):1730-1736. doi: 10.1021/acs.jmedchem.7b01609. Epub 2018 Feb 3. J Med Chem. 2018. PMID: 29378414

7

Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain.

Mostyn SN, Rawling T, Mohammadi S, Shimmon S, Frangos ZJ, Sarker S, Yousuf A, Vetter I, Ryan RM, Christie MJ, Vandenberg RJ. Mostyn SN, et al. Among authors: vetter i. J Med Chem. 2019 Mar 14;62(5):2466-2484. doi: 10.1021/acs.jmedchem.8b01775. Epub 2019 Feb 20. J Med Chem. 2019. PMID: 30714733 Free PMC article.

8

Enzymatic Ligation of a Pore Blocker Toxin and a Gating Modifier Toxin: Creating Double-Knotted Peptides with Improved Sodium Channel Na_V1.7 Inhibition.

Tran HNT, Tran P, Deuis JR, Agwa AJ, Zhang AH, Vetter I, Schroeder CI. Tran HNT, et al. Among authors: vetter i. Bioconjug Chem. 2020 Jan 15;31(1):64-73. doi: 10.1021/acs.bioconjchem.9b00744. Epub 2019 Dec 16. Bioconjug Chem. 2020. PMID: 31790574

9

Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7.

Agwa AJ, Tran P, Mueller A, Tran HNT, Deuis JR, Israel MR, McMahon KL, Craik DJ, Vetter I, Schroeder CI. Agwa AJ, et al. Among authors: vetter i. J Biol Chem. 2020 Apr 10;295(15):5067-5080. doi: 10.1074/jbc.RA119.012281. Epub 2020 Mar 5. J Biol Chem. 2020. PMID: 32139508 Free PMC article.

10

Discovery, Pharmacological Characterisation and NMR Structure of the Novel µ-Conotoxin SxIIIC, a Potent and Irreversible Na_V Channel Inhibitor.

McMahon KL, Tran HNT, Deuis JR, Lewis RJ, Vetter I, Schroeder CI. McMahon KL, et al. Among authors: vetter i. Biomedicines. 2020 Oct 2;8(10):391. doi: 10.3390/biomedicines8100391. Biomedicines. 2020. PMID: 33023152 Free PMC article.

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