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Design and Statistical Innovations in a Platform Trial for Amyotrophic Lateral Sclerosis.
Quintana M, Saville BR, Vestrucci M, Detry MA, Chibnik L, Shefner J, Berry JD, Chase M, Andrews J, Sherman AV, Yu H, Drake K, Cudkowicz M, Paganoni S, Macklin EA; HEALEY ALS Platform Trial Study Group. Quintana M, et al. Among authors: vestrucci m. Ann Neurol. 2023 Sep;94(3):547-560. doi: 10.1002/ana.26714. Epub 2023 Jun 22. Ann Neurol. 2023. PMID: 37245090
Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development.
Paganoni S, Berry JD, Quintana M, Macklin E, Saville BR, Detry MA, Chase M, Sherman AV, Yu H, Drake K, Andrews J, Shefner J, Chibnik LB, Vestrucci M, Cudkowicz ME; Healey ALS Platform Trial Study Group. Paganoni S, et al. Among authors: vestrucci m. Ann Neurol. 2022 Feb;91(2):165-175. doi: 10.1002/ana.26285. Epub 2022 Jan 10. Ann Neurol. 2022. PMID: 34935174 Review.
Analysis of sodium phenylbutyrate and taurursodiol survival effect in ALS using external controls.
Paganoni S, Quintana M, Sherman AV, Vestrucci M, Wu Y, Timmons J, Cudkowicz M; Pooled Resource Open-Access ALS Clinical Trials Consortium. Paganoni S, et al. Among authors: vestrucci m. Ann Clin Transl Neurol. 2023 Dec;10(12):2297-2304. doi: 10.1002/acn3.51915. Epub 2023 Oct 9. Ann Clin Transl Neurol. 2023. PMID: 37807839 Free PMC article. Clinical Trial.
A prospective, multi-center randomized, controlled, blinded trial of vagus nerve stimulation for difficult to treat depression: A novel design for a novel treatment.
Conway CR, Olin B, Aaronson ST, Sackeim HA, Bunker M, Kriedt C, Greco T, Broglio K, Vestrucci M, Rush AJ. Conway CR, et al. Among authors: vestrucci m. Contemp Clin Trials. 2020 Aug;95:106066. doi: 10.1016/j.cct.2020.106066. Epub 2020 Jun 19. Contemp Clin Trials. 2020. PMID: 32569757 Free article. Clinical Trial.