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A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair.
van den Heuvel D, Kim M, Wondergem AP, van der Meer PJ, Witkamp M, Lambregtse F, Kim HS, Kan F, Apelt K, Kragten A, González-Prieto R, Vertegaal ACO, Yeo JE, Kim BG, van Doorn R, Schärer OD, Luijsterburg MS. van den Heuvel D, et al. Among authors: vertegaal aco. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2208860120. doi: 10.1073/pnas.2208860120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893274 Free PMC article.
The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle.
Schimmel J, Larsen KM, Matic I, van Hagen M, Cox J, Mann M, Andersen JS, Vertegaal AC. Schimmel J, et al. Mol Cell Proteomics. 2008 Nov;7(11):2107-22. doi: 10.1074/mcp.M800025-MCP200. Epub 2008 Jun 18. Mol Cell Proteomics. 2008. PMID: 18565875 Free article.
SUMO targets the APC/C to regulate transition from metaphase to anaphase.
Eifler K, Cuijpers SAG, Willemstein E, Raaijmakers JA, El Atmioui D, Ovaa H, Medema RH, Vertegaal ACO. Eifler K, et al. Among authors: vertegaal aco. Nat Commun. 2018 Mar 16;9(1):1119. doi: 10.1038/s41467-018-03486-4. Nat Commun. 2018. PMID: 29549242 Free PMC article.
95 results