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The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.
Carmona-Gutierrez D, Zimmermann A, Kainz K, Pietrocola F, Chen G, Maglioni S, Schiavi A, Nah J, Mertel S, Beuschel CB, Castoldi F, Sica V, Trausinger G, Raml R, Sommer C, Schroeder S, Hofer SJ, Bauer MA, Pendl T, Tadic J, Dammbrueck C, Hu Z, Ruckenstuhl C, Eisenberg T, Durand S, Bossut N, Aprahamian F, Abdellatif M, Sedej S, Enot DP, Wolinski H, Dengjel J, Kepp O, Magnes C, Sinner F, Pieber TR, Sadoshima J, Ventura N, Sigrist SJ, Kroemer G, Madeo F. Carmona-Gutierrez D, et al. Among authors: ventura n. Nat Commun. 2019 Feb 19;10(1):651. doi: 10.1038/s41467-019-08555-w. Nat Commun. 2019. PMID: 30783116 Free PMC article.
Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans.
Schiavi A, Torgovnick A, Kell A, Megalou E, Castelein N, Guccini I, Marzocchella L, Gelino S, Hansen M, Malisan F, Condò I, Bei R, Rea SL, Braeckman BP, Tavernarakis N, Testi R, Ventura N. Schiavi A, et al. Among authors: ventura n. Exp Gerontol. 2013 Feb;48(2):191-201. doi: 10.1016/j.exger.2012.12.002. Epub 2012 Dec 13. Exp Gerontol. 2013. PMID: 23247094 Free PMC article.
Healthy aging: what can we learn from Caenorhabditis elegans?
Torgovnick A, Schiavi A, Maglioni S, Ventura N. Torgovnick A, et al. Among authors: ventura n. Z Gerontol Geriatr. 2013 Oct;46(7):623-8. doi: 10.1007/s00391-013-0533-5. Z Gerontol Geriatr. 2013. PMID: 23949012 Review.
Caenorhabditis elegans ATAD-3 modulates mitochondrial iron and heme homeostasis.
van den Ecker D, Hoffmann M, Müting G, Maglioni S, Herebian D, Mayatepek E, Ventura N, Distelmaier F. van den Ecker D, et al. Among authors: ventura n. Biochem Biophys Res Commun. 2015 Nov 13;467(2):389-94. doi: 10.1016/j.bbrc.2015.09.143. Epub 2015 Sep 30. Biochem Biophys Res Commun. 2015. PMID: 26427876
166 results