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STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk.
Abelson AK, Delgado-Vega AM, Kozyrev SV, Sánchez E, Velázquez-Cruz R, Eriksson N, Wojcik J, Linga Reddy MV, Lima G, D'Alfonso S, Migliaresi S, Baca V, Orozco L, Witte T, Ortego-Centeno N; AADEA group; Abderrahim H, Pons-Estel BA, Gutiérrez C, Suárez A, González-Escribano MF, Martin J, Alarcón-Riquelme ME. Abelson AK, et al. Ann Rheum Dis. 2009 Nov;68(11):1746-53. doi: 10.1136/ard.2008.097642. Epub 2008 Nov 19. Ann Rheum Dis. 2009. PMID: 19019891 Free PMC article.
WNT3A gene polymorphisms are associated with bone mineral density variation in postmenopausal mestizo women of an urban Mexican population: findings of a pathway-based high-density single nucleotide screening.
Velázquez-Cruz R, García-Ortiz H, Castillejos-López M, Quiterio M, Valdés-Flores M, Orozco L, Villarreal-Molina T, Salmerón J. Velázquez-Cruz R, et al. Age (Dordr). 2014 Jun;36(3):9635. doi: 10.1007/s11357-014-9635-2. Epub 2014 Mar 3. Age (Dordr). 2014. PMID: 24584697 Free PMC article.
PNPLA3 I148M polymorphism is associated with elevated alanine transaminase levels in Mexican Indigenous and Mestizo populations.
Larrieta-Carrasco E, Acuña-Alonzo V, Velázquez-Cruz R, Barquera-Lozano R, León-Mimila P, Villamil-Ramírez H, Menjivar M, Romero-Hidalgo S, Méndez-Sánchez N, Cárdenas V, Bañuelos-Moreno M, Flores YN, Quiterio M, Salmerón J, Sánchez-Muñoz F, Villarreal-Molina T, Aguilar-Salinas CA, Canizales-Quinteros S. Larrieta-Carrasco E, et al. Mol Biol Rep. 2014 Jul;41(7):4705-11. doi: 10.1007/s11033-014-3341-0. Epub 2014 Apr 2. Mol Biol Rep. 2014. PMID: 24691744
A genetic risk score is associated with hepatic triglyceride content and non-alcoholic steatohepatitis in Mexicans with morbid obesity.
León-Mimila P, Vega-Badillo J, Gutiérrez-Vidal R, Villamil-Ramírez H, Villareal-Molina T, Larrieta-Carrasco E, López-Contreras BE, Kauffer LR, Maldonado-Pintado DG, Méndez-Sánchez N, Tovar AR, Hernández-Pando R, Velázquez-Cruz R, Campos-Pérez F, Aguilar-Salinas CA, Canizales-Quinteros S. León-Mimila P, et al. Exp Mol Pathol. 2015 Apr;98(2):178-83. doi: 10.1016/j.yexmp.2015.01.012. Epub 2015 Jan 15. Exp Mol Pathol. 2015. PMID: 25597287
Association between PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), GCKR (rs780094), and elevated transaminase levels in overweight/obese Mexican adults.
Flores YN, Velázquez-Cruz R, Ramírez P, Bañuelos M, Zhang ZF, Yee HF Jr, Chang SC, Canizales-Quinteros S, Quiterio M, Cabrera-Alvarez G, Patiño N, Salmerón J. Flores YN, et al. Mol Biol Rep. 2016 Dec;43(12):1359-1369. doi: 10.1007/s11033-016-4058-z. Epub 2016 Oct 17. Mol Biol Rep. 2016. PMID: 27752939 Free PMC article.
107 results