Vazquez F - Search Results

1

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

Ito T, Young MJ, Li R, Jain S, Wernitznig A, Krill-Burger JM, Lemke CT, Monducci D, Rodriguez DJ, Chang L, Dutta S, Pal D, Paolella BR, Rothberg MV, Root DE, Johannessen CM, Parida L, Getz G, Vazquez F, Doench JG, Zamanighomi M, Sellers WR. Ito T, et al. Among authors: vazquez f. Nat Genet. 2021 Dec;53(12):1664-1672. doi: 10.1038/s41588-021-00967-z. Epub 2021 Dec 2. Nat Genet. 2021. PMID: 34857952

2

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.

Ramaswamy S, Nakamura N, Vazquez F, Batt DB, Perera S, Roberts TM, Sellers WR. Ramaswamy S, et al. Among authors: vazquez f. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2110-5. doi: 10.1073/pnas.96.5.2110. Proc Natl Acad Sci U S A. 1999. PMID: 10051603 Free PMC article.

3

The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.

Vazquez F, Sellers WR. Vazquez F, et al. Biochim Biophys Acta. 2000 Feb 14;1470(1):M21-35. doi: 10.1016/s0304-419x(99)00032-3. Biochim Biophys Acta. 2000. PMID: 10656987 Review. No abstract available.

4

Phosphorylation of the PTEN tail regulates protein stability and function.

Vazquez F, Ramaswamy S, Nakamura N, Sellers WR. Vazquez F, et al. Mol Cell Biol. 2000 Jul;20(14):5010-8. doi: 10.1128/MCB.20.14.5010-5018.2000. Mol Cell Biol. 2000. PMID: 10866658 Free PMC article.

5

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

Nakamura N, Ramaswamy S, Vazquez F, Signoretti S, Loda M, Sellers WR. Nakamura N, et al. Among authors: vazquez f. Mol Cell Biol. 2000 Dec;20(23):8969-82. doi: 10.1128/MCB.20.23.8969-8982.2000. Mol Cell Biol. 2000. PMID: 11073996 Free PMC article.

6

Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex.

Vazquez F, Grossman SR, Takahashi Y, Rokas MV, Nakamura N, Sellers WR. Vazquez F, et al. J Biol Chem. 2001 Dec 28;276(52):48627-30. doi: 10.1074/jbc.C100556200. Epub 2001 Nov 13. J Biol Chem. 2001. PMID: 11707428 Free article.

7

TSC2 regulates VEGF through mTOR-dependent and -independent pathways.

Brugarolas JB, Vazquez F, Reddy A, Sellers WR, Kaelin WG Jr. Brugarolas JB, et al. Among authors: vazquez f. Cancer Cell. 2003 Aug;4(2):147-58. doi: 10.1016/s1535-6108(03)00187-9. Cancer Cell. 2003. PMID: 12957289 Free article.

8

A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens.

Hsieh AC, Bo R, Manola J, Vazquez F, Bare O, Khvorova A, Scaringe S, Sellers WR. Hsieh AC, et al. Among authors: vazquez f. Nucleic Acids Res. 2004 Feb 9;32(3):893-901. doi: 10.1093/nar/gkh238. Print 2004. Nucleic Acids Res. 2004. PMID: 14769947 Free PMC article.

9

High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene.

Torres-Arzayus MI, Font de Mora J, Yuan J, Vazquez F, Bronson R, Rue M, Sellers WR, Brown M. Torres-Arzayus MI, et al. Among authors: vazquez f. Cancer Cell. 2004 Sep;6(3):263-74. doi: 10.1016/j.ccr.2004.06.027. Cancer Cell. 2004. PMID: 15380517 Free article.

10

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.

Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, Goessling W, Hahn WC. Rosenbluh J, et al. Among authors: vazquez f. Cell. 2012 Dec 21;151(7):1457-73. doi: 10.1016/j.cell.2012.11.026. Epub 2012 Dec 13. Cell. 2012. PMID: 23245941 Free PMC article.

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