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Formate induces a metabolic switch in nucleotide and energy metabolism.
Oizel K, Tait-Mulder J, Fernandez-de-Cossio-Diaz J, Pietzke M, Brunton H, Lilla S, Dhayade S, Athineos D, Blanco GR, Sumpton D, Mackay GM, Blyth K, Zanivan SR, Meiser J, Vazquez A. Oizel K, et al. Among authors: vazquez a. Cell Death Dis. 2020 May 4;11(5):310. doi: 10.1038/s41419-020-2523-z. Cell Death Dis. 2020. PMID: 32366892 Free PMC article.
Quantification of folate metabolism using transient metabolic flux analysis.
Tedeschi PM, Johnson-Farley N, Lin H, Shelton LM, Ooga T, Mackay G, Van Den Broek N, Bertino JR, Vazquez A. Tedeschi PM, et al. Among authors: vazquez a. Cancer Metab. 2015 May 28;3:6. doi: 10.1186/s40170-015-0132-6. eCollection 2015. Cancer Metab. 2015. PMID: 26023330 Free PMC article.
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Cardaci S, Zheng L, MacKay G, van den Broek NJ, MacKenzie ED, Nixon C, Stevenson D, Tumanov S, Bulusu V, Kamphorst JJ, Vazquez A, Fleming S, Schiavi F, Kalna G, Blyth K, Strathdee D, Gottlieb E. Cardaci S, et al. Among authors: vazquez a. Nat Cell Biol. 2015 Oct;17(10):1317-26. doi: 10.1038/ncb3233. Epub 2015 Aug 24. Nat Cell Biol. 2015. PMID: 26302408 Free PMC article.
Serine one-carbon catabolism with formate overflow.
Meiser J, Tumanov S, Maddocks O, Labuschagne CF, Athineos D, Van Den Broek N, Mackay GM, Gottlieb E, Blyth K, Vousden K, Kamphorst JJ, Vazquez A. Meiser J, et al. Among authors: vazquez a. Sci Adv. 2016 Oct 28;2(10):e1601273. doi: 10.1126/sciadv.1601273. eCollection 2016 Oct. Sci Adv. 2016. PMID: 27819051 Free PMC article.
DJ1 at the interface between neuro-degeneration and cancer.
Meiser J, Vazquez A, Hiller K. Meiser J, et al. Among authors: vazquez a. Oncotarget. 2017 Feb 7;8(6):9015-9016. doi: 10.18632/oncotarget.14889. Oncotarget. 2017. PMID: 28147334 Free PMC article. No abstract available.
Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.
Burgos-Barragan G, Wit N, Meiser J, Dingler FA, Pietzke M, Mulderrig L, Pontel LB, Rosado IV, Brewer TF, Cordell RL, Monks PS, Chang CJ, Vazquez A, Patel KJ. Burgos-Barragan G, et al. Among authors: vazquez a. Nature. 2017 Aug 31;548(7669):549-554. doi: 10.1038/nature23481. Epub 2017 Aug 16. Nature. 2017. PMID: 28813411 Free PMC article.
Limits of aerobic metabolism in cancer cells.
Fernandez-de-Cossio-Diaz J, Vazquez A. Fernandez-de-Cossio-Diaz J, et al. Among authors: vazquez a. Sci Rep. 2017 Oct 18;7(1):13488. doi: 10.1038/s41598-017-14071-y. Sci Rep. 2017. PMID: 29044214 Free PMC article.
1,387 results