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Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages.
Domingues N, Marques ARA, Calado RDA, Ferreira IS, Ramos C, Ramalho J, Soares MIL, Pereira T, Oliveira L, Vicente JR, Wong LH, Simões ICM, Pinho E Melo TMVD, Peden A, Almeida CG, Futter CE, Puertollano R, Vaz WLC, Vieira OV. Domingues N, et al. Among authors: vaz wlc. Traffic. 2023 Jul;24(7):284-307. doi: 10.1111/tra.12888. Epub 2023 May 2. Traffic. 2023. PMID: 37129279 Free article.
Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation.
Domingues N, Gaifem J, Matthiesen R, Saraiva DP, Bento L, Marques ARA, Soares MIL, Sampaio J, Klose C, Surma MA, Almeida MS, Rodrigues G, Gonçalves PA, Ferreira J, E Melo RG, Pedro LM, Simons K, Pinho E Melo TMVD, Cabral MG, Jacinto A, Silvestre R, Vaz W, Vieira OV. Domingues N, et al. J Lipid Res. 2023 Sep;64(9):100419. doi: 10.1016/j.jlr.2023.100419. Epub 2023 Jul 21. J Lipid Res. 2023. PMID: 37482218 Free PMC article.
Shotgun mass spectrometry-based lipid profiling identifies and distinguishes between chronic inflammatory diseases.
Matthiesen R, Lauber C, Sampaio JL, Domingues N, Alves L, Gerl MJ, Almeida MS, Rodrigues G, Araújo Gonçalves P, Ferreira J, Borbinha C, Pedro Marto J, Neves M, Batista F, Viana-Baptista M, Alves J, Simons K, Vaz WLC, Vieira OV. Matthiesen R, et al. Among authors: vaz wlc. EBioMedicine. 2021 Aug;70:103504. doi: 10.1016/j.ebiom.2021.103504. Epub 2021 Jul 24. EBioMedicine. 2021. PMID: 34311325 Free PMC article.
Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages.
Domingues N, Estronca LMBB, Silva J, Encarnação MR, Mateus R, Silva D, Santarino IB, Saraiva M, Soares MIL, Pinho E Melo TMVD, Jacinto A, Vaz WLC, Vieira OV. Domingues N, et al. Among authors: vaz wlc. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Feb;1862(2):210-220. doi: 10.1016/j.bbalip.2016.10.009. Epub 2016 Oct 26. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 27793708 Free article.
Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis.
Inácio ÂS, Domingues NS, Nunes A, Martins PT, Moreno MJ, Estronca LM, Fernandes R, Moreno AJ, Borrego MJ, Gomes JP, Vaz WL, Vieira OV. Inácio ÂS, et al. J Antimicrob Chemother. 2016 Mar;71(3):641-54. doi: 10.1093/jac/dkv405. Epub 2015 Dec 17. J Antimicrob Chemother. 2016. PMID: 26679255
39 results