Altered SPMs and age-associated decrease in brain DHA in APOE4 female mice.
Martinsen A, Tejera N, Vauzour D, Harden G, Dick J, Shinde S, Barden A, Mori TA, Minihane AM.
Martinsen A, et al. Among authors: vauzour d.
FASEB J. 2019 Sep;33(9):10315-10326. doi: 10.1096/fj.201900423R. Epub 2019 Jul 29.
FASEB J. 2019.
PMID: 31251078
Our findings show a strong association between age, female sex, and an APOE4 genotype, with decreased cortical DHA and a number of SPMs, which together may contribute to the development of cognitive decline and AD pathology.-Martinsen, A., Tejera, N., Vauzour, D., H …
Our findings show a strong association between age, female sex, and an APOE4 genotype, with decreased cortical DHA and a number of SPMs, whi …