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Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE.
Miller B, Kim SJ, Mehta HH, Cao K, Kumagai H, Thumaty N, Leelaprachakul N, Braniff RG, Jiao H, Vaughan J, Diedrich J, Saghatelian A, Arpawong TE, Crimmins EM, Ertekin-Taner N, Tubi MA, Hare ET, Braskie MN, Décarie-Spain L, Kanoski SE, Grodstein F, Bennett DA, Zhao L, Toga AW, Wan J, Yen K, Cohen P; Alzheimer’s Disease Neuroimaging Initiative*. Miller B, et al. Among authors: vaughan j. Mol Psychiatry. 2023 Apr;28(4):1813-1826. doi: 10.1038/s41380-022-01769-3. Epub 2022 Sep 21. Mol Psychiatry. 2023. PMID: 36127429 Free PMC article.
Regulation of the ER stress response by a mitochondrial microprotein.
Chu Q, Martinez TF, Novak SW, Donaldson CJ, Tan D, Vaughan JM, Chang T, Diedrich JK, Andrade L, Kim A, Zhang T, Manor U, Saghatelian A. Chu Q, et al. Among authors: vaughan jm. Nat Commun. 2019 Oct 25;10(1):4883. doi: 10.1038/s41467-019-12816-z. Nat Commun. 2019. PMID: 31653868 Free PMC article.
HtrA1 Proteolysis of ApoE In Vitro Is Allele Selective.
Chu Q, Diedrich JK, Vaughan JM, Donaldson CJ, Nunn MF, Lee KF, Saghatelian A. Chu Q, et al. Among authors: vaughan jm. J Am Chem Soc. 2016 Aug 3;138(30):9473-8. doi: 10.1021/jacs.6b03463. Epub 2016 Jul 19. J Am Chem Soc. 2016. PMID: 27379525 Free PMC article.
Insights into GLP-1 Receptor Activation with a Nonpeptide Agonist.
Martinez TF, Vaughan J, Saghatelian A. Martinez TF, et al. Among authors: vaughan j. Biochemistry. 2020 Apr 28;59(16):1549-1550. doi: 10.1021/acs.biochem.0c00180. Epub 2020 Apr 16. Biochemistry. 2020. PMID: 32297516 No abstract available.
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
Erikci Ertunc M, Kok BP, Parsons WH, Wang JG, Tan D, Donaldson CJ, Pinto AFM, Vaughan JM, Ngo N, Lum KM, Henry CL, Coppola AR, Niphakis MJ, Cravatt BF, Saez E, Saghatelian A. Erikci Ertunc M, et al. Among authors: vaughan jm. J Biol Chem. 2020 May 1;295(18):5891-5905. doi: 10.1074/jbc.RA119.012145. Epub 2020 Mar 9. J Biol Chem. 2020. PMID: 32152231 Free PMC article.
A class of anti-inflammatory lipids decrease with aging in the central nervous system.
Tan D, Konduri S, Erikci Ertunc M, Zhang P, Wang J, Chang T, Pinto AFM, Rocha A, Donaldson CJ, Vaughan JM, Ludwig RG, Willey E, Iyer M, Gray PC, Maher P, Allen NJ, Zuchero JB, Dillin A, Mori MA, Kohama SG, Siegel D, Saghatelian A. Tan D, et al. Among authors: vaughan jm. Nat Chem Biol. 2023 Feb;19(2):187-197. doi: 10.1038/s41589-022-01165-6. Epub 2022 Oct 20. Nat Chem Biol. 2023. PMID: 36266352 Free PMC article.
Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets.
DiGruccio MR, Mawla AM, Donaldson CJ, Noguchi GM, Vaughan J, Cowing-Zitron C, van der Meulen T, Huising MO. DiGruccio MR, et al. Among authors: vaughan j. Mol Metab. 2016 May 3;5(7):449-458. doi: 10.1016/j.molmet.2016.04.007. eCollection 2016 Jul. Mol Metab. 2016. PMID: 27408771 Free PMC article.
1,351 results