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Page 1
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG. Ghallab A, et al. Among authors: vartak n. J Hepatol. 2024 Feb;80(2):268-281. doi: 10.1016/j.jhep.2023.10.035. Epub 2023 Nov 7. J Hepatol. 2024. PMID: 37939855 Free PMC article.
Basic concepts of mixture toxicity and relevance for risk evaluation and regulation.
Bloch D, Diel P, Epe B, Hellwig M, Lampen A, Mally A, Marko D, Villar Fernández MA, Guth S, Roth A, Marchan R, Ghallab A, Cadenas C, Nell P, Vartak N, van Thriel C, Luch A, Schmeisser S, Herzler M, Landsiedel R, Leist M, Marx-Stoelting P, Tralau T, Hengstler JG. Bloch D, et al. Among authors: vartak n. Arch Toxicol. 2023 Nov;97(11):3005-3017. doi: 10.1007/s00204-023-03565-6. Epub 2023 Aug 24. Arch Toxicol. 2023. PMID: 37615677 Free PMC article. Review.
In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay.
Brecklinghaus T, Albrecht W, Duda J, Kappenberg F, Gründler L, Edlund K, Marchan R, Ghallab A, Cadenas C, Rieck A, Vartak N, Tolosa L, Castell JV, Gardner I, Halilbasic E, Trauner M, Ullrich A, Zeigerer A, Demirci Turgunbayer Ö, Damm G, Seehofer D, Rahnenführer J, Hengstler JG. Brecklinghaus T, et al. Among authors: vartak n. Toxicol Lett. 2022 Sep 1;368:33-46. doi: 10.1016/j.toxlet.2022.08.006. Epub 2022 Aug 10. Toxicol Lett. 2022. PMID: 35963427
Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells.
Nell P, Kattler K, Feuerborn D, Hellwig B, Rieck A, Salhab A, Lepikhov K, Gasparoni G, Thomitzek A, Belgasmi K, Blüthgen N, Morkel M, Küppers-Munther B, Godoy P, Hay DC, Cadenas C, Marchan R, Vartak N, Edlund K, Rahnenführer J, Walter J, Hengstler JG. Nell P, et al. Among authors: vartak n. J Hepatol. 2022 Nov;77(5):1386-1398. doi: 10.1016/j.jhep.2022.07.009. Epub 2022 Jul 19. J Hepatol. 2022. PMID: 35863491 Free article.
Reply.
Vartak N, Elferink RO, van de Graaf S, Drasdo D, Hengstler J. Vartak N, et al. Hepatology. 2022 Sep;76(3):E58. doi: 10.1002/hep.32485. Epub 2022 Apr 5. Hepatology. 2022. PMID: 35344603 No abstract available.
Reply.
Vartak N, Hengstler JG. Vartak N, et al. Hepatology. 2022 Apr;75(4):1061-1062. doi: 10.1002/hep.32297. Epub 2022 Jan 11. Hepatology. 2022. PMID: 34953145 No abstract available.
The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds.
Brecklinghaus T, Albrecht W, Kappenberg F, Duda J, Vartak N, Edlund K, Marchan R, Ghallab A, Cadenas C, Günther G, Leist M, Zhang M, Gardner I, Reinders J, Russel FG, Foster AJ, Williams DP, Damle-Vartak A, Grandits M, Ecker G, Kittana N, Rahnenführer J, Hengstler JG. Brecklinghaus T, et al. Among authors: vartak n. Chem Biol Interact. 2022 Jan 5;351:109728. doi: 10.1016/j.cbi.2021.109728. Epub 2021 Oct 27. Chem Biol Interact. 2022. PMID: 34717914 Free article.
Reply.
Vartak N, Hengstler JG. Vartak N, et al. Hepatology. 2022 Feb;75(2):493-494. doi: 10.1002/hep.32168. Epub 2021 Dec 7. Hepatology. 2022. PMID: 34546585 No abstract available.
41 results