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CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.
Nat Biotechnol. 2008 May;26(5):549-51. doi: 10.1038/nbt1399. Epub 2008 Apr 27.
Nat Biotechnol. 2008.
PMID: 18438402
Free article.
Review.
Identification of transfected cell types following non-viral gene transfer to the murine lung.
Davies LA, Seguela C, Varathalingam A, Cheng SH, Hyde SC, Gill DR.
Davies LA, et al. Among authors: varathalingam a.
J Gene Med. 2007 Mar;9(3):184-96. doi: 10.1002/jgm.1007.
J Gene Med. 2007.
PMID: 17351986
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Electroporation enhances reporter gene expression following delivery of naked plasmid DNA to the lung.
Pringle IA, McLachlan G, Collie DD, Sumner-Jones SG, Lawton AE, Tennant P, Baker A, Gordon C, Blundell R, Varathalingam A, Davies LA, Schmid RA, Cheng SH, Porteous DJ, Gill DR, Hyde SC.
Pringle IA, et al. Among authors: varathalingam a.
J Gene Med. 2007 May;9(5):369-80. doi: 10.1002/jgm.1026.
J Gene Med. 2007.
PMID: 17410613
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Adenovirus-mediated in utero expression of CFTR does not improve survival of CFTR knockout mice.
Davies LA, Varathalingam A, Painter H, Lawton AE, Sumner-Jones SG, Nunez-Alonso GA, Chan M, Munkonge F, Alton EW, Hyde SC, Gill DR.
Davies LA, et al. Among authors: varathalingam a.
Mol Ther. 2008 May;16(5):812-8. doi: 10.1038/mt.2008.25. Epub 2008 Mar 11.
Mol Ther. 2008.
PMID: 18388934
Free article.
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Limitations of the murine nose in the development of nonviral airway gene transfer.
Griesenbach U, Sumner-Jones SG, Holder E, Munkonge FM, Wodehouse T, Smith SN, Wasowicz MY, Pringle I, Casamayor I, Chan M, Coles R, Cornish N, Dewar A, Doherty A, Farley R, Green AM, Jones BL, Larsen MD, Lawton AE, Manvell M, Painter H, Singh C, Somerton L, Stevenson B, Varathalingam A, Siegel C, Scheule RK, Cheng SH, Davies JC, Porteous DJ, Gill DR, Boyd AC, Hyde SC, Alton EW.
Griesenbach U, et al. Among authors: varathalingam a.
Am J Respir Cell Mol Biol. 2010 Jul;43(1):46-54. doi: 10.1165/rcmb.2009-0075OC. Epub 2009 Jul 31.
Am J Respir Cell Mol Biol. 2010.
PMID: 19648474
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Long-term persistence of gene expression from adeno-associated virus serotype 5 in the mouse airways.
Sumner-Jones SG, Davies LA, Varathalingam A, Gill DR, Hyde SC.
Sumner-Jones SG, et al. Among authors: varathalingam a.
Gene Ther. 2006 Dec;13(24):1703-13. doi: 10.1038/sj.gt.3302815. Epub 2006 Jul 20.
Gene Ther. 2006.
PMID: 16855618
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