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The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer.
Patel SA, Hirosue S, Rodrigues P, Vojtasova E, Richardson EK, Ge J, Syafruddin SE, Speed A, Papachristou EK, Baker D, Clarke D, Purvis S, Wesolowski L, Dyas A, Castillon L, Caraffini V, Bihary D, Yong C, Harrison DJ, Stewart GD, Machiela MJ, Purdue MP, Chanock SJ, Warren AY, Samarajiwa SA, Carroll JS, Vanharanta S. Patel SA, et al. Among authors: vanharanta s. Nature. 2022 Jun;606(7916):999-1006. doi: 10.1038/s41586-022-04809-8. Epub 2022 Jun 8. Nature. 2022. PMID: 35676472 Free PMC article.
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.
Tuupanen S, Turunen M, Lehtonen R, Hallikas O, Vanharanta S, Kivioja T, Björklund M, Wei G, Yan J, Niittymäki I, Mecklin JP, Järvinen H, Ristimäki A, Di-Bernardo M, East P, Carvajal-Carmona L, Houlston RS, Tomlinson I, Palin K, Ukkonen E, Karhu A, Taipale J, Aaltonen LA. Tuupanen S, et al. Among authors: vanharanta s. Nat Genet. 2009 Aug;41(8):885-90. doi: 10.1038/ng.406. Epub 2009 Jun 28. Nat Genet. 2009. PMID: 19561604
Therapy-induced tumour secretomes promote resistance and tumour progression.
Obenauf AC, Zou Y, Ji AL, Vanharanta S, Shu W, Shi H, Kong X, Bosenberg MC, Wiesner T, Rosen N, Lo RS, Massagué J. Obenauf AC, et al. Among authors: vanharanta s. Nature. 2015 Apr 16;520(7547):368-72. doi: 10.1038/nature14336. Epub 2015 Mar 25. Nature. 2015. PMID: 25807485 Free PMC article.
Epigenetic determinants of metastasis.
Patel SA, Vanharanta S. Patel SA, et al. Among authors: vanharanta s. Mol Oncol. 2017 Jan;11(1):79-96. doi: 10.1016/j.molonc.2016.09.008. Epub 2016 Oct 8. Mol Oncol. 2017. PMID: 27756687 Free PMC article. Review.
NF-κB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis.
Rodrigues P, Patel SA, Harewood L, Olan I, Vojtasova E, Syafruddin SE, Zaini MN, Richardson EK, Burge J, Warren AY, Stewart GD, Saeb-Parsy K, Samarajiwa SA, Vanharanta S. Rodrigues P, et al. Among authors: vanharanta s. Cancer Discov. 2018 Jul;8(7):850-865. doi: 10.1158/2159-8290.CD-17-1211. Epub 2018 Jun 6. Cancer Discov. 2018. PMID: 29875134 Free PMC article.
VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function.
Briston T, Stephen JM, Thomas LW, Esposito C, Chung YL, Syafruddin SE, Turmaine M, Maddalena LA, Greef B, Szabadkai G, Maxwell PH, Vanharanta S, Ashcroft M. Briston T, et al. Among authors: vanharanta s. Front Oncol. 2018 Oct 4;8:388. doi: 10.3389/fonc.2018.00388. eCollection 2018. Front Oncol. 2018. PMID: 30338240 Free PMC article.
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