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The lipid flippase ATP10B enables cellular lipid uptake under stress conditions.
Wouters R, Beletchi I, Van den Haute C, Baekelandt V, Martin S, Eggermont J, Vangheluwe P. Wouters R, et al. Among authors: vangheluwe p. Biochim Biophys Acta Mol Cell Res. 2024 Feb;1871(2):119652. doi: 10.1016/j.bbamcr.2023.119652. Epub 2023 Dec 11. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 38086447 Review.
Thapsigargin affinity purification of intracellular P(2A)-type Ca(2+) ATPases.
Vandecaetsbeek I, Christensen SB, Liu H, Van Veldhoven PP, Waelkens E, Eggermont J, Raeymaekers L, Møller JV, Nissen P, Wuytack F, Vangheluwe P. Vandecaetsbeek I, et al. Among authors: vangheluwe p. Biochim Biophys Acta. 2011 May;1813(5):1118-27. doi: 10.1016/j.bbamcr.2010.12.020. Epub 2011 Jan 4. Biochim Biophys Acta. 2011. PMID: 21215281 Free article.
A lipid switch unlocks Parkinson's disease-associated ATP13A2.
Holemans T, Sørensen DM, van Veen S, Martin S, Hermans D, Kemmer GC, Van den Haute C, Baekelandt V, Günther Pomorski T, Agostinis P, Wuytack F, Palmgren M, Eggermont J, Vangheluwe P. Holemans T, et al. Among authors: vangheluwe p. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9040-5. doi: 10.1073/pnas.1508220112. Epub 2015 Jul 1. Proc Natl Acad Sci U S A. 2015. PMID: 26134396 Free PMC article.
Unlocking ATP13A2/PARK9 activity.
Martin S, Holemans T, Vangheluwe P. Martin S, et al. Among authors: vangheluwe p. Cell Cycle. 2015;14(21):3341-2. doi: 10.1080/15384101.2015.1093420. Cell Cycle. 2015. PMID: 26392192 Free PMC article. No abstract available.
A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency.
Tharkeshwar AK, Trekker J, Vermeire W, Pauwels J, Sannerud R, Priestman DA, Te Vruchte D, Vints K, Baatsen P, Decuypere JP, Lu H, Martin S, Vangheluwe P, Swinnen JV, Lagae L, Impens F, Platt FM, Gevaert K, Annaert W. Tharkeshwar AK, et al. Among authors: vangheluwe p. Sci Rep. 2017 Jan 30;7:41408. doi: 10.1038/srep41408. Sci Rep. 2017. PMID: 28134274 Free PMC article.
Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78).
Estrada-Cuzcano A, Martin S, Chamova T, Synofzik M, Timmann D, Holemans T, Andreeva A, Reichbauer J, De Rycke R, Chang DI, van Veen S, Samuel J, Schöls L, Pöppel T, Mollerup Sørensen D, Asselbergh B, Klein C, Zuchner S, Jordanova A, Vangheluwe P, Tournev I, Schüle R. Estrada-Cuzcano A, et al. Among authors: vangheluwe p. Brain. 2017 Feb;140(2):287-305. doi: 10.1093/brain/aww307. Brain. 2017. PMID: 28137957 Free PMC article.
Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a).
Chen J, De Raeymaecker J, Hovgaard JB, Smaardijk S, Vandecaetsbeek I, Wuytack F, Møller JV, Eggermont J, De Maeyer M, Christensen SB, Vangheluwe P. Chen J, et al. Among authors: vangheluwe p. J Biol Chem. 2017 Apr 28;292(17):6938-6951. doi: 10.1074/jbc.M117.778431. Epub 2017 Mar 6. J Biol Chem. 2017. PMID: 28264934 Free PMC article.
83 results