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A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models.
Mol Cancer Ther. 2024 Jan 3;23(1):3-13. doi: 10.1158/1535-7163.MCT-22-0681.
Mol Cancer Ther. 2024.
PMID: 37748190
Mechanism of action of phthalazinone derivatives against rabies virus.
Perraud V, Vanderhoydonck B, Bouvier G, Dias de Melo G, Kilonda A, Koukni M, Jochmans D, Rogée S, Ben Khalifa Y, Kergoat L, Lannoy J, Van Buyten T, Izadi-Pruneyre N, Chaltin P, Neyts J, Marchand A, Larrous F, Bourhy H.
Perraud V, et al. Among authors: vanderhoydonck b.
Antiviral Res. 2024 Apr;224:105838. doi: 10.1016/j.antiviral.2024.105838. Epub 2024 Feb 18.
Antiviral Res. 2024.
PMID: 38373533
Free article.
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Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo.
Reuberson J, Horsley H, Franklin RJ, Ford D, Neuss J, Brookings D, Huang Q, Vanderhoydonck B, Gao LJ, Jang MY, Herdewijn P, Ghawalkar A, Fallah-Arani F, Khan AR, Henshall J, Jairaj M, Malcolm S, Ward E, Shuttleworth L, Lin Y, Li S, Louat T, Waer M, Herman J, Payne A, Ceska T, Doyle C, Pitt W, Calmiano M, Augustin M, Steinbacher S, Lammens A, Allen R.
Reuberson J, et al. Among authors: vanderhoydonck b.
J Med Chem. 2018 Aug 9;61(15):6705-6723. doi: 10.1021/acs.jmedchem.8b00521. Epub 2018 Jul 19.
J Med Chem. 2018.
PMID: 29952567
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Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis.
Kögler M, Vanderhoydonck B, De Jonghe S, Rozenski J, Van Belle K, Herman J, Louat T, Parchina A, Sibley C, Lescrinier E, Herdewijn P.
Kögler M, et al. Among authors: vanderhoydonck b.
J Med Chem. 2011 Jul 14;54(13):4847-62. doi: 10.1021/jm2004688. Epub 2011 Jun 9.
J Med Chem. 2011.
PMID: 21657202
Free article.
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Synthesis and antibacterial evaluation of a novel series of 2-(1,2-dihydro-3-oxo-3H-pyrazol-2-yl)benzothiazoles.
Stella A, Segers K, De Jonghe S, Vanderhoydonck B, Rozenski J, Anné J, Herdewijn P.
Stella A, et al. Among authors: vanderhoydonck b.
Chem Biodivers. 2011 Feb;8(2):253-65. doi: 10.1002/cbdv.201000241.
Chem Biodivers. 2011.
PMID: 21337499
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Discovery of 7-N-piperazinylthiazolo[5,4-d]pyrimidine analogues as a novel class of immunosuppressive agents with in vivo biological activity.
Jang MY, Lin Y, De Jonghe S, Gao LJ, Vanderhoydonck B, Froeyen M, Rozenski J, Herman J, Louat T, Van Belle K, Waer M, Herdewijn P.
Jang MY, et al. Among authors: vanderhoydonck b.
J Med Chem. 2011 Jan 27;54(2):655-68. doi: 10.1021/jm101254z. Epub 2010 Dec 20.
J Med Chem. 2011.
PMID: 21171614
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Synthesis of highly functionalised spiro-indoles by a halogen atom transfer radical cyclization.
Stevens CV, Van Meenen E, Eeckhout Y, Vanderhoydonck B, Hooghe W.
Stevens CV, et al. Among authors: vanderhoydonck b.
Chem Commun (Camb). 2005 Oct 14;(38):4827-9. doi: 10.1039/b508424e. Epub 2005 Sep 2.
Chem Commun (Camb). 2005.
PMID: 16193128
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Conjugate addition to 1-phosphono-2-aza-1,3-butadienes: synthesis of phosphonylated gamma-lactams.
Vanderhoydonck B, Stevens CV.
Vanderhoydonck B, et al.
J Org Chem. 2005 Jan 7;70(1):191-8. doi: 10.1021/jo0488661.
J Org Chem. 2005.
PMID: 15624922
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