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Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade.
Awad RM, Lecocq Q, Zeven K, Ertveldt T, De Beck L, Ceuppens H, Broos K, De Vlaeminck Y, Goyvaerts C, Verdonck M, Raes G, Van Parys A, Cauwels A, Keyaerts M, Devoogdt N, Breckpot K. Awad RM, et al. Among authors: van parys a. Mol Ther Methods Clin Dev. 2021 Jun 4;22:172-182. doi: 10.1016/j.omtm.2021.05.017. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34485603 Free PMC article.
Delivering Type I Interferon to Dendritic Cells Empowers Tumor Eradication and Immune Combination Treatments.
Cauwels A, Van Lint S, Paul F, Garcin G, De Koker S, Van Parys A, Wueest T, Gerlo S, Van der Heyden J, Bordat Y, Catteeuw D, Rogge E, Verhee A, Vandekerckhove B, Kley N, Uzé G, Tavernier J. Cauwels A, et al. Among authors: van lint s, van parys a, van der heyden j. Cancer Res. 2018 Jan 15;78(2):463-474. doi: 10.1158/0008-5472.CAN-17-1980. Epub 2017 Nov 29. Cancer Res. 2018. PMID: 29187401
Safe eradication of large established tumors using neovasculature-targeted tumor necrosis factor-based therapies.
Huyghe L, Van Parys A, Cauwels A, Van Lint S, De Munter S, Bultinck J, Zabeau L, Hostens J, Goethals A, Vanderroost N, Verhee A, Uzé G, Kley N, Peelman F, Vandekerckhove B, Brouckaert P, Tavernier J. Huyghe L, et al. Among authors: van lint s, van parys a. EMBO Mol Med. 2020 Feb 7;12(2):e11223. doi: 10.15252/emmm.201911223. Epub 2020 Jan 8. EMBO Mol Med. 2020. PMID: 31912630 Free PMC article.
A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state.
Van Lint S, Van Parys A, Van Den Eeckhout B, Vandamme N, Plaisance S, Verhee A, Catteeuw D, Rogge E, De Geest J, Vanderroost N, Roels J, Saeys Y, Uzé G, Kley N, Cauwels A, Tavernier J. Van Lint S, et al. Among authors: van parys a. Mol Cancer. 2023 Nov 29;22(1):191. doi: 10.1186/s12943-023-01908-6. Mol Cancer. 2023. PMID: 38031106 Free PMC article.
Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly.
De Munter S, Van Parys A, Bral L, Ingels J, Goetgeluk G, Bonte S, Pille M, Billiet L, Weening K, Verhee A, Van der Heyden J, Taghon T, Leclercq G, Kerre T, Tavernier J, Vandekerckhove B. De Munter S, et al. Among authors: van parys a, van der heyden j. Int J Mol Sci. 2020 Jan 30;21(3):883. doi: 10.3390/ijms21030883. Int J Mol Sci. 2020. PMID: 32019116 Free PMC article.
T-2 toxin induced Salmonella Typhimurium intoxication results in decreased Salmonella numbers in the cecum contents of pigs, despite marked effects on Salmonella-host cell interactions.
Verbrugghe E, Vandenbroucke V, Dhaenens M, Shearer N, Goossens J, De Saeger S, Eeckhout M, D'Herde K, Thompson A, Deforce D, Boyen F, Leyman B, Van Parys A, De Backer P, Haesebrouck F, Croubels S, Pasmans F. Verbrugghe E, et al. Among authors: van parys a. Vet Res. 2012 Mar 22;43(1):22. doi: 10.1186/1297-9716-43-22. Vet Res. 2012. PMID: 22440148 Free PMC article.
49 results