Van Lanen SG - Search Results

1

Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2.

Wang X, Elshahawi SI, Cai W, Zhang Y, Ponomareva LV, Chen X, Copley GC, Hower JC, Zhan CG, Parkin S, Rohr J, Van Lanen SG, Shaaban KA, Thorson JS. Wang X, et al. Among authors: van lanen sg. J Nat Prod. 2017 Apr 28;80(4):1141-1149. doi: 10.1021/acs.jnatprod.7b00108. Epub 2017 Mar 30. J Nat Prod. 2017. PMID: 28358212 Free PMC article.

2

Antitumor antibiotics: bleomycin, enediynes, and mitomycin.

Galm U, Hager MH, Van Lanen SG, Ju J, Thorson JS, Shen B. Galm U, et al. Among authors: van lanen sg. Chem Rev. 2005 Feb;105(2):739-58. doi: 10.1021/cr030117g. Chem Rev. 2005. PMID: 15700963 No abstract available.

3

Delineating the earliest steps of gilvocarcin biosynthesis: role of GilP and GilQ in starter unit specificity.

Shepherd MD, Kharel MK, Zhu LL, van Lanen SG, Rohr J. Shepherd MD, et al. Among authors: van lanen sg. Org Biomol Chem. 2010 Sep 7;8(17):3851-6. doi: 10.1039/c0ob00036a. Epub 2010 Jul 8. Org Biomol Chem. 2010. PMID: 20617244

4

Characterization of LipL as a non-heme, Fe(II)-dependent α-ketoglutarate:UMP dioxygenase that generates uridine-5'-aldehyde during A-90289 biosynthesis.

Yang Z, Chi X, Funabashi M, Baba S, Nonaka K, Pahari P, Unrine J, Jacobsen JM, Elliott GI, Rohr J, Van Lanen SG. Yang Z, et al. Among authors: van lanen sg. J Biol Chem. 2011 Mar 11;286(10):7885-7892. doi: 10.1074/jbc.M110.203562. Epub 2011 Jan 7. J Biol Chem. 2011. PMID: 21216959 Free PMC article.

5

Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis.

Pahari P, Kharel MK, Shepherd MD, van Lanen SG, Rohr J. Pahari P, et al. Among authors: van lanen sg. Angew Chem Int Ed Engl. 2012 Jan 27;51(5):1216-20. doi: 10.1002/anie.201105882. Epub 2011 Dec 23. Angew Chem Int Ed Engl. 2012. PMID: 22223167 Free PMC article. No abstract available.

6

Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway.

Tibrewal N, Downey TE, Van Lanen SG, Ul Sharif E, O'Doherty GA, Rohr J. Tibrewal N, et al. Among authors: van lanen sg. J Am Chem Soc. 2012 Aug 1;134(30):12402-5. doi: 10.1021/ja305113d. Epub 2012 Jul 19. J Am Chem Soc. 2012. PMID: 22800463 Free PMC article.

7

Cooperation of two bifunctional enzymes in the biosynthesis and attachment of deoxysugars of the antitumor antibiotic mithramycin.

Wang G, Pahari P, Kharel MK, Chen J, Zhu H, Van Lanen SG, Rohr J. Wang G, et al. Among authors: van lanen sg. Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10638-42. doi: 10.1002/anie.201205414. Epub 2012 Sep 20. Angew Chem Int Ed Engl. 2012. PMID: 22997042 Free PMC article.

8

Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase.

Barnard-Britson S, Chi X, Nonaka K, Spork AP, Tibrewal N, Goswami A, Pahari P, Ducho C, Rohr J, Van Lanen SG. Barnard-Britson S, et al. Among authors: van lanen sg. J Am Chem Soc. 2012 Nov 14;134(45):18514-7. doi: 10.1021/ja308185q. Epub 2012 Nov 2. J Am Chem Soc. 2012. PMID: 23110675 Free PMC article.

9

Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues.

Singh S, Zhang J, Huber TD, Sunkara M, Hurley K, Goff RD, Wang G, Zhang W, Liu C, Rohr J, Van Lanen SG, Morris AJ, Thorson JS. Singh S, et al. Among authors: van lanen sg. Angew Chem Int Ed Engl. 2014 Apr 7;53(15):3965-9. doi: 10.1002/anie.201308272. Epub 2014 Mar 11. Angew Chem Int Ed Engl. 2014. PMID: 24616228 Free PMC article.

10

The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.

Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, Van Lanen SG. Cai W, et al. Among authors: van lanen sg. J Biol Chem. 2015 May 29;290(22):13710-24. doi: 10.1074/jbc.M115.646414. Epub 2015 Apr 8. J Biol Chem. 2015. PMID: 25855790 Free PMC article.

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