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Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse model.
Goossens C, Weckx R, Derde S, Van Helleputte L, Schneidereit D, Haug M, Reischl B, Friedrich O, Van Den Bosch L, Van den Berghe G, Langouche L. Goossens C, et al. Among authors: van helleputte l. J Cachexia Sarcopenia Muscle. 2021 Apr;12(2):443-455. doi: 10.1002/jcsm.12668. Epub 2021 Jan 19. J Cachexia Sarcopenia Muscle. 2021. PMID: 33465304 Free PMC article.
HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.
Benoy V, Van Helleputte L, Prior R, d'Ydewalle C, Haeck W, Geens N, Scheveneels W, Schevenels B, Cader MZ, Talbot K, Kozikowski AP, Vanden Berghe P, Van Damme P, Robberecht W, Van Den Bosch L. Benoy V, et al. Among authors: van helleputte l. Brain. 2018 Mar 1;141(3):673-687. doi: 10.1093/brain/awx375. Brain. 2018. PMID: 29415205 Free PMC article.
C-kit is important for SOD1(G93A) mouse survival independent of mast cells.
Staats KA, Schönefeldt S, Van Helleputte L, Van Rillaer M, Lampi Y, Dooley J, Van Den Bosch L, Liston A. Staats KA, et al. Among authors: van helleputte l. Neuroscience. 2015 Aug 20;301:415-20. doi: 10.1016/j.neuroscience.2015.06.026. Epub 2015 Jun 23. Neuroscience. 2015. PMID: 26112382
Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth.
Van Helleputte L, Kater M, Cook DP, Eykens C, Rossaert E, Haeck W, Jaspers T, Geens N, Vanden Berghe P, Gysemans C, Mathieu C, Robberecht W, Van Damme P, Cavaletti G, Jarpe M, Van Den Bosch L. Van Helleputte L, et al. Neurobiol Dis. 2018 Mar;111:59-69. doi: 10.1016/j.nbd.2017.11.011. Epub 2017 Nov 29. Neurobiol Dis. 2018. PMID: 29197621 Free article.
Genetic ablation of phospholipase C delta 1 increases survival in SOD1(G93A) mice.
Staats KA, Van Helleputte L, Jones AR, Bento-Abreu A, Van Hoecke A, Shatunov A, Simpson CL, Lemmens R, Jaspers T, Fukami K, Nakamura Y, Brown RH Jr, Van Damme P, Liston A, Robberecht W, Al-Chalabi A, Van Den Bosch L. Staats KA, et al. Among authors: van damme p, van helleputte l, van den bosch l, van hoecke a. Neurobiol Dis. 2013 Dec;60:11-7. doi: 10.1016/j.nbd.2013.08.006. Epub 2013 Aug 19. Neurobiol Dis. 2013. PMID: 23969236
Testosterone boosts physical activity in male mice via dopaminergic pathways.
Jardí F, Laurent MR, Kim N, Khalil R, De Bundel D, Van Eeckhaut A, Van Helleputte L, Deboel L, Dubois V, Schollaert D, Decallonne B, Carmeliet G, Van den Bosch L, D'Hooge R, Claessens F, Vanderschueren D. Jardí F, et al. Among authors: van helleputte l. Sci Rep. 2018 Jan 17;8(1):957. doi: 10.1038/s41598-017-19104-0. Sci Rep. 2018. PMID: 29343749 Free PMC article.
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