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Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Joyce MG, Zhang B, Ou L, Chen M, Chuang GY, Druz A, Kong WP, Lai YT, Rundlet EJ, Tsybovsky Y, Yang Y, Georgiev IS, Guttman M, Lees CR, Pancera M, Sastry M, Soto C, Stewart-Jones GBE, Thomas PV, Van Galen JG, Baxa U, Lee KK, Mascola JR, Graham BS, Kwong PD. Joyce MG, et al. Among authors: van galen jg. Nat Struct Mol Biol. 2016 Sep;23(9):811-820. doi: 10.1038/nsmb.3267. Epub 2016 Aug 1. Nat Struct Mol Biol. 2016. PMID: 27478931 Free PMC article.
Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains.
Joyce MG, Georgiev IS, Yang Y, Druz A, Geng H, Chuang GY, Kwon YD, Pancera M, Rawi R, Sastry M, Stewart-Jones GBE, Zheng A, Zhou T, Choe M, Van Galen JG, Chen RE, Lees CR, Narpala S, Chambers M, Tsybovsky Y, Baxa U, McDermott AB, Mascola JR, Kwong PD. Joyce MG, et al. Among authors: van galen jg. Cell Rep. 2017 Dec 5;21(10):2992-3002. doi: 10.1016/j.celrep.2017.11.016. Cell Rep. 2017. PMID: 29212041 Free article.
Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.
Georgiev IS, Joyce MG, Chen RE, Leung K, McKee K, Druz A, Van Galen JG, Kanekiyo M, Tsybovsky Y, Yang ES, Yang Y, Acharya P, Pancera M, Thomas PV, Wanninger T, Yassine HM, Baxa U, Doria-Rose NA, Cheng C, Graham BS, Mascola JR, Kwong PD. Georgiev IS, et al. Among authors: van galen jg. ACS Infect Dis. 2018 May 11;4(5):788-796. doi: 10.1021/acsinfecdis.7b00192. Epub 2018 Mar 6. ACS Infect Dis. 2018. PMID: 29451984
Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape.
Wang L, Shi W, Chappell JD, Joyce MG, Zhang Y, Kanekiyo M, Becker MM, van Doremalen N, Fischer R, Wang N, Corbett KS, Choe M, Mason RD, Van Galen JG, Zhou T, Saunders KO, Tatti KM, Haynes LM, Kwong PD, Modjarrad K, Kong WP, McLellan JS, Denison MR, Munster VJ, Mascola JR, Graham BS. Wang L, et al. Among authors: van galen jg. J Virol. 2018 Apr 27;92(10):e02002-17. doi: 10.1128/JVI.02002-17. Print 2018 May 15. J Virol. 2018. PMID: 29514901 Free PMC article.
Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B.
Joyce MG, Bao A, Chen M, Georgiev IS, Ou L, Bylund T, Druz A, Kong WP, Peng D, Rundlet EJ, Van Galen JG, Wang S, Yang Y, Zhang B, Chuang GY, McLellan JS, Graham BS, Mascola JR, Kwong PD. Joyce MG, et al. Among authors: van galen jg. Pathog Immun. 2019 Dec 11;4(2):294-323. doi: 10.20411/pai.v4i2.338. eCollection 2019. Pathog Immun. 2019. PMID: 31893251 Free PMC article.
Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.
Georgiev IS, Joyce MG, Yang Y, Sastry M, Zhang B, Baxa U, Chen RE, Druz A, Lees CR, Narpala S, Schön A, Van Galen J, Chuang GY, Gorman J, Harned A, Pancera M, Stewart-Jones GB, Cheng C, Freire E, McDermott AB, Mascola JR, Kwong PD. Georgiev IS, et al. J Virol. 2015 May;89(10):5318-29. doi: 10.1128/JVI.03451-14. Epub 2015 Mar 4. J Virol. 2015. PMID: 25740988 Free PMC article.