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Universal antibody targeting the highly conserved fusion peptide provides cross-protection in mice.
Muralidharan A, Gravel C, Harris G, Hashem AM, Zhang W, Safronetz D, Van Domselaar G, Krammer F, Sauve S, Rosu-Myles M, Wang L, Chen W, Li X. Muralidharan A, et al. Among authors: van domselaar g. Hum Vaccin Immunother. 2022 Nov 30;18(5):2083428. doi: 10.1080/21645515.2022.2083428. Epub 2022 Jun 20. Hum Vaccin Immunother. 2022. PMID: 35724343 Free PMC article.
Universal anti-neuraminidase antibody inhibiting all influenza A subtypes.
Doyle TM, Hashem AM, Li C, Van Domselaar G, Larocque L, Wang J, Smith D, Cyr T, Farnsworth A, He R, Hurt AC, Brown EG, Li X. Doyle TM, et al. Among authors: van domselaar g. Antiviral Res. 2013 Nov;100(2):567-74. doi: 10.1016/j.antiviral.2013.09.018. Epub 2013 Sep 30. Antiviral Res. 2013. PMID: 24091204
A monoclonal antibody targeting a highly conserved epitope in influenza B neuraminidase provides protection against drug resistant strains.
Doyle TM, Li C, Bucher DJ, Hashem AM, Van Domselaar G, Wang J, Farnsworth A, She YM, Cyr T, He R, Brown EG, Hurt AC, Li X. Doyle TM, et al. Among authors: van domselaar g. Biochem Biophys Res Commun. 2013 Nov 8;441(1):226-9. doi: 10.1016/j.bbrc.2013.10.041. Epub 2013 Oct 16. Biochem Biophys Res Commun. 2013. PMID: 24140051
124 results