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An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons.
Cukier HN, Duarte CL, Laverde-Paz MJ, Simon SA, Van Booven DJ, Miyares AT, Whitehead PL, Hamilton-Nelson KL, Adams LD, Carney RM, Cuccaro ML, Vance JM, Pericak-Vance MA, Griswold AJ, Dykxhoorn DM. Cukier HN, et al. Among authors: van booven dj. Neurobiol Aging. 2023 Nov;131:182-195. doi: 10.1016/j.neurobiolaging.2023.07.007. Epub 2023 Jul 17. Neurobiol Aging. 2023. PMID: 37677864 Free article.
mitoTALEN reduces the mutant mtDNA load in neurons.
Bacman SR, Barrera-Paez JD, Pinto M, Van Booven D, Stewart JB, Griswold AJ, Moraes CT. Bacman SR, et al. Mol Ther Nucleic Acids. 2024 Feb 2;35(1):102132. doi: 10.1016/j.omtn.2024.102132. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2024. PMID: 38404505 Free PMC article.
An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons.
Cukier HN, Duarte CL, Laverde-Paz MJ, Simon SA, Van Booven DJ, Miyares AT, Whitehead PL, Hamilton-Nelson KL, Adams LD, Carney RM, Cuccaro ML, Vance JM, Pericak-Vance MA, Griswold AJ, Dykxhoorn DM. Cukier HN, et al. Among authors: van booven dj. bioRxiv [Preprint]. 2023 May 25:2023.05.25.542316. doi: 10.1101/2023.05.25.542316. bioRxiv. 2023. PMID: 37292815 Free PMC article. Updated. Preprint.
Targeting long non-coding RNA NUDT6 enhances smooth muscle cell survival and limits vascular disease progression.
Winter H, Winski G, Busch A, Chernogubova E, Fasolo F, Wu Z, Bäcklund A, Khomtchouk BB, Van Booven DJ, Sachs N, Eckstein HH, Wittig I, Boon RA, Jin H, Maegdefessel L. Winter H, et al. Among authors: van booven dj. Mol Ther. 2023 Jun 7;31(6):1775-1790. doi: 10.1016/j.ymthe.2023.04.020. Epub 2023 May 5. Mol Ther. 2023. PMID: 37147804 Free PMC article.
35 results