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Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors.
Gorecki L, Misiachna A, Damborsky J, Dolezal R, Korabecny J, Cejkova L, Hakenova K, Chvojkova M, Karasova JZ, Prchal L, Novak M, Kolcheva M, Kortus S, Vales K, Horak M, Soukup O. Gorecki L, et al. Among authors: vales k. Eur J Med Chem. 2021 Jul 5;219:113434. doi: 10.1016/j.ejmech.2021.113434. Epub 2021 Apr 20. Eur J Med Chem. 2021. PMID: 33892271 Free article.
The pharmacology of tacrine at N-methyl-d-aspartate receptors.
Horak M, Holubova K, Nepovimova E, Krusek J, Kaniakova M, Korabecny J, Vyklicky L, Kuca K, Stuchlik A, Ricny J, Vales K, Soukup O. Horak M, et al. Among authors: vales k. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Apr 3;75:54-62. doi: 10.1016/j.pnpbp.2017.01.003. Epub 2017 Jan 13. Prog Neuropsychopharmacol Biol Psychiatry. 2017. PMID: 28089695 Review.
7-Methoxyderivative of tacrine is a 'foot-in-the-door' open-channel blocker of GluN1/GluN2 and GluN1/GluN3 NMDA receptors with neuroprotective activity in vivo.
Kaniakova M, Kleteckova L, Lichnerova K, Holubova K, Skrenkova K, Korinek M, Krusek J, Smejkalova T, Korabecny J, Vales K, Soukup O, Horak M. Kaniakova M, et al. Among authors: vales k. Neuropharmacology. 2018 Sep 15;140:217-232. doi: 10.1016/j.neuropharm.2018.08.010. Epub 2018 Aug 9. Neuropharmacology. 2018. PMID: 30099049
Orexin supplementation in narcolepsy treatment: A review.
Nepovimova E, Janockova J, Misik J, Kubik S, Stuchlik A, Vales K, Korabecny J, Mezeiova E, Dolezal R, Soukup O, Kobrlova T, Pham NL, Nguyen TD, Konecny J, Kuca K. Nepovimova E, et al. Among authors: vales k. Med Res Rev. 2019 May;39(3):961-975. doi: 10.1002/med.21550. Epub 2018 Nov 14. Med Res Rev. 2019. PMID: 30426515 Review.
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.
Chalupova K, Korabecny J, Bartolini M, Monti B, Lamba D, Caliandro R, Pesaresi A, Brazzolotto X, Gastellier AJ, Nachon F, Pejchal J, Jarosova M, Hepnarova V, Jun D, Hrabinova M, Dolezal R, Zdarova Karasova J, Mzik M, Kristofikova Z, Misik J, Muckova L, Jost P, Soukup O, Benkova M, Setnicka V, Habartova L, Chvojkova M, Kleteckova L, Vales K, Mezeiova E, Uliassi E, Valis M, Nepovimova E, Bolognesi ML, Kuca K. Chalupova K, et al. Among authors: vales k. Eur J Med Chem. 2019 Apr 15;168:491-514. doi: 10.1016/j.ejmech.2019.02.021. Epub 2019 Feb 27. Eur J Med Chem. 2019. PMID: 30851693
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